找到约 55 条 “HU6” 相关结果 （用时 0.096 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M40805
|
Recombinant Human TPO (HEK293, N,C-6His) | 重组人TPO (HEK293, N,C-6His) | Cytokines and Growth Factors |
| Thrombopoietin; THPO | |||
| Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. | |||
| M5726
|
Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His) | 重组人CD48/SLAMF2蛋白 (HEK293,C-Fc-6His) | Cytokines and Growth Factors |
| CD48 antigen; B-lymphocyte activation marker BLAST-1 | |||
| Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. | |||
| M11359
|
Recombinant Human IL-6R (CHO) | 重组人IL-6R (CHO) | Cytokines and Growth Factors |
| IL-6RA; IL-6R1; CD126; IL-6RA | |||
| 白细胞介素-6受体α 属于I型细胞因子受体家族。重组人Interleukin-6R（IL-6R）在含有10.0 ng/ml 人IL-6的M1细胞中，通过细胞增殖实验测得的ED50为 < 0.2 μg/ml。 | |||
| M10548
|
TSPC | TSPC | GSK-3 |
| HUN86320 | |||
| TSPC (HUN86320)是一种糖原合成酶激酶-3β抑制剂(GSK-3β Inhibitor)。 | |||
| M25585
|
Recombinant Human HMGB1 Protein (HEK293, C-6His) | 重组人HMGB1蛋白 (HEK293, C-6His) | Other Proteins |
| High Mobility Group Protein B1 | |||
| High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. | |||
| M9364
|
Recombinant human IL-6 (CHO-expressed) | 重组人白介素6 | Cytokines and Growth Factors |
| Interleukin-6; rhIL-6 | |||
| 重组人白介素6（Recombinant Human IL-6）是由纤维母细胞、单核、巨噬细胞、T 淋巴细胞、B 淋巴细胞、上皮细胞、角质细胞、以及多种瘤细胞所产生。 | |||
M9413
|
Recombinant Human VEGF165 Protein (HEK293, C-His) | 重组人VEGF165蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。 | |||
| M9983
|
Recombinant Human IL-36RA Protein (E. coli) | 重组人IL-36RA蛋白 (E. coli) | Cytokines and Growth Factors |
| Interleukin-36RA; IL-1F5; IL-1-Related Protein 3 | |||
| 重组人IL-36RA蛋白（rhIL-36RA）原名 rhIL-1F5，可通过与 IL-1Rrp2 受体结合，拮抗 IL-36α，β或γ诱导的 NF-RrpB 信号传导，从而阻止功能信号的启动。 | |||
| M10512
|
Recombinant Human IL-6 (E. coli) | 重组人IL-6蛋白（E. coli） | Cytokines and Growth Factors |
| rHuIL-6 | |||
| 重组人白介素6（Recombinant Human IL-6）是一种在人类中由 IL-6 基因编码的白细胞介素，可作为促炎和抗炎细胞因子，有效诱导肝细胞合成急性期蛋白，参与炎症反应。 | |||
| M15052
|
Recombinant Human 4-1BB Ligand/TNFSF (E.coli,C-6His) | 重组人4-1BB Ligand/TNFSF蛋白 (E.coli,C-6His) | Cytokines and Growth Factors |
| Tumor necrosis factor ligand superfamily member 9; | |||
| 重组人4-1BB配体由大肠杆菌表达系统产生，编码Arg71-Glu254的目的基因在c端以6His标记表达。Accession #: P41273。 | |||
| M11319
|
GLP-1(7-36), amide TFA | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | |||
| GLP-1(7-36), amide TFA 是一种主要的肠道激素，在葡萄糖的刺激下，它能促使胰岛 β 细胞分泌胰岛素。 | |||
| M11383
|
Anti-human CD16 mAb | 抗人CD16单克隆抗体 | Cytokines and Growth Factors |
| 生物活性：CD16分子 即FcγR Ⅲ，分子量为50～70kD的糖蛋白, 属Ig 超家族成员，已知参与抗体依赖性的细胞毒性（ADCC）作用，其最显著的特征在于膜受体负责触发的裂解是由 NK 细胞完成的。 | |||
| M11490
|
Recombinant Human VEGF165 (P. pastoris) | 重组人VEGF165 (P. pastoris) | Cytokines and Growth Factors |
| VEGF-165; Vascular Endothelial Growth Factor 165; VPF | |||
| 血管内皮生长因子 (VEGF) 是一种有效的生长和血管生成细胞因子。它刺激内皮细胞的增殖和存活，并促进血管生成和血管通透性。 | |||
| M13400
|
Recombinant Human UBA5 (E.coli, N-6His) | 重组人UBA5 蛋白 (E.coli,N-6His) | Cytokines and Growth Factors |
| Ubiquitin-like modifier-activating enzyme 5 | |||
| UBA5是泛素激活E1家族和UBA5亚家族的成员之一。泛素和泛素样蛋白被识别为通过三步酶途径与各种细胞底物共价结合。泛素激活酶(E1)在泛素化途径激活泛素或泛素样蛋白的第一步起着至关重要的作用。 | |||
| M13968
|
GLP-1(7-36), amide acetate | GLP-1(7-36), amide acetate | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | |||
| GLP-1(7-36), amide acetate 是一种主要的肠道激素，在葡萄糖的刺激下，它能促使胰岛 β 细胞分泌胰岛素。 | |||
| M15015
|
Recombinant Human Carbonic Anhydrase 1/CA1 (E.coli,C-6His) | 重组人Carbonic Anhydrase 1/CA1蛋白(E.coli,C-6His) | Cytokines and Growth Factors |
| Carbonate Dehydratase I; Carbonic Anhydrase B | |||
| 重组人Carbonic Anhydrase 1/CA1蛋白由我们的大肠杆菌表达系统产生，编码Ala2-Phe261的目的基因在c端以6His标记表达。Accession #: P00915。 | |||
| M15014
|
Recombinant Human Carboxypeptidase M (HEK293,C-6His) | 重组人Carboxypeptidase M (HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase M;CPM | |||
| Carboxypeptidase M (CPM) plays important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. It is widely distributed in a variety of tissues and cells. | |||
| M15012
|
Recombinant Human TIMP-2 (HEK293,C-6His) | 重组人TIMP-2蛋白（HEK293,C-6His） | Cytokines and Growth Factors |
| Metalloproteinase Inhibitor 2; CSC-21K | |||
| TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. | |||
| M15018
|
Recombinant Human ACE-2 (HEK293,C-6His) | 重组人ACE-2蛋白 (HEK293,C-6His) | Cytokines and Growth Factors |
| Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase | |||
| 血管紧张素转换酶 2 (Angiotensin-Converting Enzyme 2, ACE-2) 是一种整合的膜蛋白和 ACE 家族的锌金属蛋白酶，ACE-2 将血管紧张素 I 和 II 切割为羧肽酶，ACE-2 将血管紧张素 I 转化为血管紧张素 1-9，将血管紧张素 II 转化为血管紧张素 1-7。ACE-2 还能够高效水解 apelin-13 和 dynorphin-13。 | |||
| M15008
|
Recombinant Human Carboxypeptidase E/CPE (HEK293,C-6His) | 重组人Carboxypeptidase E/CPE蛋白(HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase H; Enkephalin convertase | |||
| CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. | |||
| M15066
|
Recombinant Human FGF-basic (146 aa, E.coli) | 重组人FGF-basic蛋白 (146 aa, E.coli) | Cytokines and Growth Factors |
| Fibroblast growth factor 2; FGF-2; bFGF | |||
| FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. FGF-basic acts on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. | |||
| M15072
|
Recombinant Human FGF-19 (E.coli, N-6His) | 重组人FGF-19蛋白 (E.coli, N-6His) | Cytokines and Growth Factors |
| Fibroblast growth factor 19; FGF-19; FGF19 | |||
| 重组人成纤维细胞生长因子19由大肠杆菌表达系统产生，编码Phe27-Lys216的目的基因在n端以6His标记表达。Accession #: O95750。 | |||
| M15073
|
Recombinant Human HGF (HEK293, C-6His) | 重组人HGF蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| Hepatocyte growth factor; HPTA; Scatter factor | |||
| HGF is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. | |||
| M15080
|
Recombinant Human OSM (E.coli, N-6His) | 重组人OSM蛋白 (E.coli, N-6His) | Cytokines and Growth Factors |
| Oncostatin-M; OSM | |||
| 重组人Oncostatin M由大肠杆菌表达系统产生，编码Ala26-Arg221的目的基因在n端以6His标记表达。通过对TF-1细胞的剂量依赖性刺激来测定的ED50是0.2-1 ng/ml。 | |||
| M15098
|
Recombinant Human PCSK9 (HEK293,C-6His) | 重组人PCSK9 蛋白 (HEK293,C-6His) | Cytokines and Growth Factors |
| Proprotein Convertase Subtilisin/Kexin Type 9 | |||
| Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. Accession #: Q8NBP7. | |||
| M19977
|
Recombinant Human PRCP (HEK293, C-6His) | 重组人PRCP 蛋白(HEK293, C-6His) | Cytokines and Growth Factors |
| Lysosomal Pro-X Carboxypeptidase; Angiotensinase C | |||
| Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. Accession: P42785. | |||
| M19986
|
Recombinant Human CXCL6 (HEK293, C-6His) | 重组人CXCL6 蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | |||
| Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162. | |||
| M19993
|
Recombinant Human B4GALT1 (HEK293, C-6His) | 重组人B4GALT1 蛋白(HEK293, C-6His) | Cytokines and Growth Factors |
| 1,4- galactosyltransferase, polypeptide 1; B4GalT1 | |||
| Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291. | |||
| M20739 | TRi-1 | TRi-1 | Others |
| HUN20688, TXNRD1 inhibitor 1 | |||
| TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic thioredoxin reductase 1 (TXNRD1) inhibitor with IC50 of 12 nM. TRi-1 exhibits anti-cancer activity while having little mitochondrial toxicity. | |||
| M21202
|
Recombinant Human Lipocalin-2/NGAL/LCN2 (E. coli, C-6His) | 重组人Lipocalin-2/NGAL/LCN2 蛋白 (E. coli, C-6His) | Cytokines and Growth Factors |
| Neutrophil gelatinase-associated lipocalin; NGAL | |||
| 人中性粒细胞明胶酶相关脂质运载蛋白(Lipocalin-2/NGAL/LCN2)由大肠杆菌表达系统生产，编码Gln21-Gly198的目标基因在C端有一个6His标签。Protein number：P80188。 | |||
| M40855
|
Recombinant Human Siglec-7 Protein (HEK293, C-6His) | 重组人Siglec-7蛋白 (HEK293, C-6His) | Receptor Proteins |
| sialic acid binding Ig-like lectin 7; CD328 antigen; p75/AIRM1; QA79 | |||
| Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. It binds equally well to both alpha 2,3- and alpha 2,6-linked sialic acid. | |||
| M4391
|
Isoimperatorin | 异欧前胡素；白芷甲素；异欧芹属素乙 | AChR/AChE |
| Isoimperatorin 是Angelica dahurica 根的甲醇提取物，有效抑制乙酰胆碱酯酶 (AChE)，IC50 为 74.6 μM。 | |||
| M4425
|
3-Butylidenephthalide | 丁烯基苯酞 | Parasite |
| Butylidenephthalide | |||
| 3-Butylidenephthalide (Butylidenephthalide) 是一种从 Ligusticum chuanxiong Hort 鉴定的邻苯二甲酸酐衍生物，具有杀虫活性 (对 Spodoptera litura larvae 的 LC50 值为 1.56 mg/g)。 | |||
| M4520
|
(+)-Corydaline | 延胡索甲素 | AChR/AChE |
| (+)-Corydaline; Corydalin | |||
| Corydaline ((+)-Corydaline) 是一种从 Corydalis yanhusuo 提取的异喹啉生物碱，是一种 AChE 抑制剂，IC50 为 226 µM。Corydaline 是一种 μ 阿片受体 (μ-opioid receptor, Ki 为 1.23 µM) 激动剂，可抑制肠道病毒 71 (EV71) 复制 (IC50 为 25.23 µM)。Corydaline 具有抗血管生成，抗过敏，胃排空和抗伤害感受的作用。 | |||
| M11353
|
6‴-Feruloylspinosin | 6-阿魏酰斯皮诺素 | GABA Receptor |
| 6‴-Feruloylspinosin 是从 Ziziphus jujuba 种子中分离出的一种类黄酮。在大鼠海马神经元中，6‴-Feruloylspinosin 能透过血脑屏障，增强 GABAAα1、GABAAα5、GABABR1 的 mRNA 表达。 | |||
| M8200 | SB 220025 trihydrochloride | SB 220025 trihydrochloride | Others |
| SB 220025 is a potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase, with an IC50 value of 60 nM and 50- to 1000-fold selectivity. | |||
| M8277
|
680C91 | 680C91 | COX |
| 680C91是一种有效的色氨酸2，3-双加氧酶2(TDO 2)抑制剂，Ki值为51 nM，同时可通过浓度依赖性的方式诱导SK-Mel-28和HUVEC细胞停滞在G2期，从而抑制细胞增殖。此外，680C91还能下调子宫蜕膜细胞中Cox2和Vegf基因的表达。 | |||
| M9106
|
ST-193 | ST-193 | Anti-infection |
| ST193 | |||
| ST-193是一种有效的广谱arenavirus抑制剂，其抑制Guanarito，Junin，Lassa和Machupo病毒的IC50值分别为0.44，0.62，1.4和3.1 nM。 | |||
| M10458
|
Huwentoxin IV TFA | Huwentoxin IV TFA | Sodium Channel |
| Huwentoxin-IV | |||
| Huwentoxin IV TFA 是一种有效的，选择性的钠通道阻滞剂，它抑制神经元 Nav1.7，Nav1.2，Nav1.3 和 Nav1.4的IC50 值分别为 26、150、338 和 400 nM。 | |||
| M10683
|
IMB-301 | IMB-301 | HIV Protease |
| IMB-301 是一种特异性的 HIV-1 复制抑制剂，能与 hA3G (human APOBEC3G) 结合，阻断 hA3G-Vif 相互作用，抑制 Vif 介导的 hA3G 降解。IMB-301 抑制 H9 细胞中 HIV-1 的复制 (IC50=8.63 uM)。人 APOBEC3G 是一种抑制 HIV-1 复制的限制因子。 | |||
| M11386
|
Recombinant Human CD19 Protein (HEK293) | 重组人CD19蛋白，GMP级 (HEK293) | Cytokines and Growth Factors |
| Recombinant Human CD19 Protein (HEK293) 蛋白序列：DNA 序列编码人 CD19 (UniProtKB/Swiss-Prot: P15391.6)表达带有 His 标签在 C 末端。 生物活性：固定 CD19 的单抗 at 5μg/mL (100 μL/孔) ，能够结合 CD19 蛋白的线性范围是 5-100ng/mL | |||
| M13479 | (Z)-Ligustilide | 藁本内酯 | Antibiotic |
| (Z)-Ligustilide 是从 Ligusticum chuanxiong Hort 中提取的，具有抗菌和抗真菌活性，抗真菌评分为 5.6。 (Z)-Ligustilide 抑制 FATP5 和 DGAT 的表达，抑制小鼠脂肪酸的摄取和酯化，具有研究非酒精性脂肪性肝病 (NAFLD) 的潜力。 | |||
| M14308
|
SID 26681509 quarterhydrate | SID 26681509 quarterhydrate | Cathepsin |
| SID 26681509 quarterhydrate 是一种有效的，可逆的，竞争性的，选择性的人组织蛋白酶 L (human cathepsin L) 抑制剂，IC50 为 56 nM。SID 26681509 quarterhydrate 抑制 Plasmodium falciparum 的体外繁殖，并抑制 Leishmania major，IC50 分别为 15.4 μM 和 12.5 μM。SID 26681509 quarterhydrate 对组织蛋白酶 G 没有抑制活性。 | |||
| M14441 | JHU-083 | JHU-083 | Others |
| JHU-083 是 6-diazo-5-oxo-L-norleucine 的前体，是一种口服有效的，选择性的谷氨酰胺酶 (glutaminase) 拮抗剂，可阻断脑 CD11b+ 细胞和实验性脑疟疾 (ECM) 中的谷氨酰胺酶，导致动物中谷氨酸水平的净降低。 | |||
| M14479
|
Sacubitril | 沙库必曲 | Neprilysin (NEP) |
| AHU-377 | |||
| Sacubitril (AHU-377) 是有效的脑啡肽酶（NEP）抑制剂，IC50值为5 nM。此外，Sacubitril 还是 LCZ696 的一个组分。 | |||
| M40924
|
Recombinant Human IL31RA Protein (HEK293, C-hFc) | 重组人IL31RA蛋白 (HEK293, C-hFc) | Cytokines and Growth Factors |
| interleukin 31 receptor A | |||
| The recombinant human IL31RA consists 735 amino acids and predicts a molecular mass of 83.5 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with the Fc region of human IgG1 at the C-terminus. | |||
| M40923
|
Recombinant Human IL31RA Protein (HEK293, C-His) | 重组人IL31RA蛋白 (HEK293, C-His) | Cytokines and Growth Factors |
| interleukin 31 receptor A | |||
| The recombinant human IL31RA consists 508 amino acids and predicts a molecular mass of 58.2 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with a polyhistidine tag at the C-terminus. | |||
| M20707
|
RK 24466 | RK 24466 | Src-bcr-Abl |
| KIN 001-51, Lck inhibitor C 8863, C8863 | |||
| RK-24466 (KIN 001-51) is a potent and selective inhibitor of Lck that inhibits two constructs of the human lck kinase, lck (64-509) and lckcd with IC50 of < 0.001 μM and 0.002 μM, respectively. | |||
| M20713 | DMX-5084 | DMX-5084 | MAPKAPK2/MAP3K/MAP4K |
| DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively. | |||
| M20749 | TP0463518 | TP0463518 | HIF |
| TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. | |||
| M20810 | PBD-150 | PBD-150 | Amyloid |
| PBD-150 is a potent human glutaminyl cyclase (hQC) Y115E-Y117E variant inhibitor with Ki of 60 nM. | |||
| M20981 | BI-671800 | BI-671800 | Prostaglandin Receptor |
| AP-761, Cmpd A | |||
| BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS. | |||
| M21212
|
Recombinant Human Arylsulfatase A/ARSA (HEK293, C-6His) | 重组人Arylsulfatase A/ARSA蛋白 (HEK293, C-6His) | Cytokines and Growth Factors |
| Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA | |||
| Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, Recombinant Human Arylsulfatase A/ARSA expressed the target gene encoding Arg19-Ala507 with a 6His tag at the C-terminus. | |||
| M21684
|
Recombinant Human MMP-3 (HEK293, C-6His) | 重组人MMP-3 蛋白(HEK293, C-6His) | Enzymes & Regulators |
| Matrix metalloproteinase-3 | |||
| Recombinant Human MMP-3是基质金属蛋白酶 (MMP) 家族的成员，参与正常生理过程中细胞外基质的分解，由哺乳动物表达系统产生，编码 Tyr18-Cys477 的靶基因在 C 末端用 6His 标签表达。酶原需要被胰凝乳蛋白酶激活以获得激活形式。 | |||
| M21685
|
Recombinant Human MMP-1 (HEK293, C-6His) | 重组人MMP-1 蛋白(HEK293, C-6His) | Enzymes & Regulators |
| Matrix Metalloproteinase-1 | |||
| Recombinant Human MMP-1可降解多种底物，包括 I、II、III、VII、VIII 和 X 型胶原蛋白以及酪蛋白、明胶、α1 抗胰蛋白酶、髓磷脂碱性蛋白、L-选择蛋白、pro-TNF、IL1、IGFBP3 、IGFBP5、pro-MMP2 和 pro-MMP9。Recombinant Human Matrix Metalloproteinase-1 由哺乳动物表达系统产生，编码 Phe20-Asn469 的靶基因在 C 末端用 6His 标签表达。酶原需要被 APMA 激活以获得激活形式。 | |||
