—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Recombinant Human TPO (Mammalian, N,C-6His) 重组人TPO (Mammalian, N,C-6His)

目录号 M40805 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets.

Recombinant Human TPO (Mammalian, N,C-6His)结构式

别名:Thrombopoietin; THPO

规格 价格 库存状态
10ug ¥ 2340 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.01 EU/μg
  • COA
  • MSDS
生物活性

Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. Thrombopoietin (TPO) produced by the liver and kidney which regulates the production of platelets.

Recombinant Human Thrombopoietin is produced by Mammalian expression system and expressed the target gene encoding Ser22-Gly353 with a 6His tag at the N-terminus, 6His tag at the C-terminus.


Accession: P40225

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: 70-90 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Mathilde Tjepkema et al. Crit Rev Oncol Hematol. Risk of thrombosis with thrombopoietin receptor agonists for ITP patients: A systematic review and meta-analysis

[2] Jeffrey Gilreath et al. Drugs. Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists

[3] Hanny Al-Samkari et al. Expert Rev Hematol. Clinical challenges and promising therapies for chemotherapy-induced thrombocytopenia

[4] Ian S Hitchcock et al. Br J Haematol. Thrombopoietin from beginning to end

[5] T Kotani. Rinsho Byori. [Anti-TPO autoantibodies]

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.

Recombinant Human USP14 (E.coli, N-6His)

USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.





关键词:Recombinant Human TPO (Mammalian, N,C-6His), Thrombopoietin; THPO, Recombinant Human TPO (Mammalian, N,C-6His)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human TPO (Mammalian, N,C-6His), Recombinant Human TPO (Mammalian, N,C-6His)溶解度, Recombinant Human TPO (Mammalian, N,C-6His)结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号