—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

最新产品


查看按时间排序的100个最新产品
目录号 产品名称 产品简介
M55398 ER-Tracker Green ER-Tracker探针是一系列具有细胞膜透过性,对活细胞内质网具有高度选择性的探针,且对细胞几乎无毒性。本品为ER-Tracker Green,由绿色荧光染料BODIPY FL和 Glibenclamide 偶联而成,其Ex= 504 nm,Em= 511nm。Glibenclamide 是一种 ATP 依赖性 K+ 通道阻滞剂 (Kir6, KATP) 和 CFTR Cl-通道阻滞剂,在内质网中发生结合。ER-Tracker 不适合对固定后细胞进行染色。
M55397 Recombinant Human HMGB1 Protein (E. coli) High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
M55396 Black 96-Well Cell Culture Plates with Clear Bottom, TC-treated 黑色透明底96孔细胞培养板 (TC处理) 简称96孔黑色底透板。本产品是最常用的细胞培养板之一,细胞贴壁性优良,主要适用于贴壁细胞的培养和荧光的检测(Fluorescent assay)等。
M55395 Patulin Patulin (Terinin,棒曲霉素) 是一种由多种霉菌产生的真菌毒素,有致染色体断裂、突变,致畸和细胞毒性作用。Patulin 通过溶酶体-线粒体轴诱导自噬依赖性细胞凋亡,能引起 DNA 损伤。
M55394 T-2 Toxin T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌毒素。T-2 Toxin (T-2 Mycotoxin) 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑制剂,抑制 DNA 和 RNA 的合成,干扰膜磷脂的代谢,并增加肝脏脂质过氧化物的水平。
M55393 DAR-2 DAR-2 是一种灵敏的 NO 荧光指示剂。
M55392 ZnAF-2 DA ZnAF-2 DA 是一种荧光 Zn2+ 探针,适用于检测 Zn2+(酯酶水解后)。激发492nm,发射515nm
M55391 ZnAF-1 ZnAF-1 是一种基于荧光素的锌传感器 (zinc sensor),含有 N,N-双(2-吡啶甲基)乙二胺螯合单元,可以用来做 Zn2+ 的检测。
M55390 Fluorescein octadecyl ester Fluorescein octadecyl ester 是一种亲脂性荧光 pH 指示剂。Fluorescein octadecyl ester 是一种亲脂性荧光试剂,固定在塑化的 PVC 膜上。Fluorescein octadecyl ester 可以可逆地识别酒精分子,可用于测定酒精饮料中乙醇的浓度。
M55389 HPTS HPTS 是一种荧光膜渗透型 pH 指示剂。Ex: 460nm, Em: 510nm
M55388 2-Iminobiotin 2-Iminobiotin (Guanidinobiotin) 是一种生物素 (维生素 H 或 B7) 类似物。2-Iminobiotin 是一种可逆的 NO 合酶抑制剂,作用于小鼠 iNOS 和大鼠 n-cNOS,Ki 值分别为 21.8 和 37.5 μM。2-Iminobiotin 与低温环境可保护人类神经细胞免受缺氧诱导的细胞损伤。
M55387 2-Iminobiotin hydrobromide 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) 是一种生物素 (维生素 H 或 B7) 类似物。2-Iminobiotin hydrobromide 是一种可逆的 NO 合酶抑制剂,作用于小鼠 iNOS 和大鼠 n-cNOS,Ki 值分别为 21.8 和 37.5 μM。2-Iminobiotin hydrobromide 与低温环境可保护人类神经细胞免受缺氧诱导的细胞损伤。
M55386 Glutathione monoethyl ester Glutathione monoethyl ester谷胱甘肽乙酯具有细胞渗透性,可用于保护细胞免受辐射损伤、氧化剂和包括重金属在内的各种有毒化合物的伤害。Glutathione monoethyl ester谷胱甘肽乙酯是 GSH 的衍生物,可用于部分补充半胱氨酸和/或 GSH 贫乏细胞内的 GSH 供应。
M55385 DAR-1 DAR-1 是一种灵敏的 NO 荧光探针。激发566nm,发射586nm
M55384 Dispase 中性蛋白酶是由枯草芽孢杆菌经发酵提取而得的,属于一种内切酶,可用于各种蛋白质水解处理。
M55383 N-Methylnicotinamide N-Methylnicotinamide (MNA, Nicotinyl Methylamide, N-Methyl-3-pyridinecarboxamide) 是一种活性内源性代谢产物,可通过调节ADMA-DDAH轴改善内皮功能障碍并减轻动脉粥样硬化。
M55382 Recombinant Human IL-25/IL-17E (E. coli, C-His) Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation.
M55381 Recombinant Human IL-25/IL-17E (Mammalian, C-6His) Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation.
M55380 Recombinant Human SEMA3A (Mammalian, N-6His-Flag) Semaphorin 3A (SEMA3A) is a secreted protein which belongs to the semaphorin family. Semaphorin 3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites.
M55379 Beta-Hydroxyisovaleric acid Beta-Hydroxyisovaleric acid (β-羟基异戊酸) 是尿液中排泄的正常内源性代谢产物 (endogenous metabolite)。
M55378 HFIP 六氟异丙醇 (HFIP) 是一种极性强氢键供给溶剂,可与水和有机溶剂混溶且热稳定性好,可用于制备含氟表面活性剂、含氟乳化剂等多种化学品,以及作为溶剂或清洗剂。HFIP可以溶解很大一部分的聚合物,如聚酯、聚酰胺、聚丙烯腈、聚缩醛和水解聚乙烯酯等,由于这样的性质使其能够在分析方面得到很好的应用及作为高聚物再利用的再生剂。
M55377 2-Bromo-2'-methoxyacetophenone 2-Bromo-2'-methoxyacetophenone 2-溴-2'-甲氧基苯乙酮
M55376 Gly-Pro-pNA hydrochloride Gly-Pro-pNA hydrochloride 是一种二肽基肽酶抑制剂,对二肽基肽酶II、二肽基肽酶IV和二肽基肽酶IX具有抑制作用。Gly-Pro-pNA 是一种显色底物,可被循环酶二肽基肽酶 IV (DPP IV) 切割,可用于筛选 DPP IV 抑制剂。
M55375 Recombinant Human CD143/ACE (E. coli, N-GST) CD143/ACE Protein is a recombinant human Angiotensin I-converting enzyme (ACE, CD143) which hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity.
M55374 Recombinant Human Neprilysin (Mammalian, N-8His) Neprilysin/CD10 (MME; NEP) is a zinc metallopeptidase expressed at the cell surface of a variety of cells. Neprilysin/CD10 (MME) has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide.
M55373 Recombinant Human THOP1 (E.coli, C-6His) Thimet Oligopeptidase (THOP1) is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
M55372 Ketodeoxynonulosonic acid Ketodeoxynonulosonic acid (KDN; 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid) 是一种唾液酸,KDN 保护寡/(聚)唾液酸链免受非还原端外切唾液酸酶的影响,并在鲑科鱼的卵激活中发挥作用。
M55371 Choline Choline胆碱是所有生物膜的组成成分和胆碱能神经元中的乙酰胆碱的前体。胆碱有促进脑发育和提高记忆能力;保证信息传递;调控细胞凋亡;构成生物膜的重要组成成分;促进脂肪代谢;促进体内转甲基代谢和降低血清胆固醇的作用。
M55370 Methyl Green Methyl Green 是一种有效的荧光染料。Methyl Green 是细胞和电泳凝胶的 DNA 染色剂。Methyl Green 可以通过显微镜和流式细胞术直接测定活性,峰值在 633 和 677 nm。
M55369 Ammonium iron(II) sulfate Ammonium iron(II) sulfate 硫酸亚铁铵在分析化学中用以配制亚铁离子标准溶液;是一种蓝绿色的无机复盐。
M55368 2-Hydroxy Fluorene 2-Hydroxy Fluorene 在生命科学相关研究中具有广泛的应用。
M55367 2-Naphthol 2-Naphthol 是 naphthalene 的代谢物,由细胞色素 P450 亚型 (CYP 1A1,CYP 1A2,CYP 2A1,CYP 2E1 和 CYP 2F2) 催化而成。
M55366 Isoluminol Isoluminol (异鲁米诺) 是一种化学发光试剂,也可作为生物材料或有机化合物,用于生命科学相关研究。鲁米诺类试剂因具有较高的发光量子产率和较好的水溶性,可与多种氧化剂发生化学反应,已成为应用最广泛的化学发光试剂。
M55365 Apomorphine hydrochloride hemihydrate Apomorphine hydrochloride hemihydrate 是一种多巴胺D2激动剂。
M55364 Recombinant Mouse IL-22 (Mammalian, C-mFc) Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins.
M55363 IDE397 IDE397 (GSK-4362676) 是一种潜在“first-in-class”的甲硫氨酸腺苷转移酶2A(MAT2A)抑制剂。IDE397 (GSK-4362676) 在 MTAP 缺失的 PDX 模型中表现出抗肿瘤活性。
M55362 Recombinant Human REG4 Protein (Mammalian, C-6His) Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.
M55361 Recombinant Mouse REG4 Protein (HEK293, His Tag) Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.
M55360 4-Methylumbelliferyl phosphate 4-Methylumbelliferyl phosphate (4-MUP) 是一种阴离子有机磷酸酯,是一种酸性和碱性磷酸酶 (phosphatase) 的荧光底物。
M55359 Mirzotamab clezutoclax Mirzotamab clezutoclax 是一种首创的靶向B7H3的ADC。Mirzotamab clezutoclax 与细胞表面的B7H3结合,导致ADC内化、连接体裂解以及细胞内有效载荷的释放,从而导致细胞凋亡。
M55358 Qingdainone Qingdainone 是一种天然产物,可从 Qingdai 中获得。Qingdainone 具有研究抗肿瘤和抗炎的潜力。
M55357 BMS-566394 BMS-566394 是一种强效的 TNF-α 转换酶(TACE)特异选择性抑制剂。
M55356 Bis-PEG2-acid Bis-PEG2-acid (COOH-PEG1-COOH) 是一种 PROTAC linker,属于 PEG 类。Bis-PEG1-propionic acid 可用于合成一系列 PROTAC 分子。
M55355 Recombinant Mouse IGF-1 (E.coli, C-6His) Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.
M55354 2-aminoindan-2-phosphonic acid 2-aminoindan-2-phosphonic acid (AIP,2-氨基茚满-2-膦酸)
M55353 Recombinant Human BMP-9 Protein (E. coli, His Tag) Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1.
M55352 3-Chloro-L-tyrosine 3-Chloro-L-tyrosine 是一种髓过氧化物酶催化氧化中的特异性标记,3-Chloro-L-tyrosine 在人类动脉粥样硬化内膜分离出的低密度脂蛋白中明显升高。
M55351 Recombinant Human IL-4 Protein (Mammalian) Interleukin-4 (IL-4) regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes.
M55350 Recombinant Human IL-13 Protein (Mammalian, C-Fc) Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells.
M55349 n-Dodecyl α-D-maltoside n-Dodecyl α-D-maltoside is a nonionic detergent commonly used to solubilize integral membrane proteins and protein complexes. It has a critical micelle concentration (CMC) of 0.15 mM. n-Dodecyl α-D-maltoside has been used to solubilize photosystem I (PSI) and PSII complexes from plant thylakoid membranes, as well as intact grana.
M55348 5-(chloromethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole 5-(chloromethyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole
M55347 5-Chloromethyl-3-(4-fluoro-phenyl)-[1,2,4]oxadiazole 5-Chloromethyl-3-(4-fluoro-phenyl)-[1,2,4]oxadiazole
M55346 5-(chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole 5-(chloromethyl)-3-(4-chlorophenyl)-1,2,4-oxadiazole
M55345 5-(chloromethyl)-3-(4-methylphenyl)-1,2,4-oxadiazole 5-(chloromethyl)-3-(4-methylphenyl)-1,2,4-oxadiazole
M55344 5-(chloromethyl)-3-(furan-2-yl)-1,2,4-oxadiazole 5-(chloromethyl)-3-(furan-2-yl)-1,2,4-oxadiazole
M55343 5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole 5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole
M55342 Percoll Percoll 是一种用于细胞、病毒和亚细胞颗粒密度梯度离心的经典培养基。Percoll 由直径为15-30 nm(在水中为23% w/w)并涂覆有聚乙烯吡咯烷酮(PVP)的胶体二氧化硅颗粒组成。它被用来建立无毒低粘度,低渗透压密度梯度,可用于分离细胞,细胞器和病毒。它已被用来分离 大肠杆菌的内外膜泡。 Percoll在整个梯度过程中都是等渗的,无毒,并且很容易从纯化的材料中去除。
M55341 Gliadin Gliadin 麦醇溶蛋白是发现于谷类(如小麦、黑麦等)种子中的一组蛋白质混合物。分为两大类(α/β和γ),其组成和性质相似。富含脯氨酸,贮存小麦种子中的大部分蛋白质。
M55340 Tris(2-chloroethyl) phosphate Tris(2-chloroethyl) phosphate (TCEP) 是一种典型的有机磷系阻燃剂。
M55339 Phosphotungstic acid Phosphotungstic acid 磷钨酸 可以用于细胞标本的组织学染色。Phosphotungstic acid 磷钨酸 可用作透射电子显微镜(TEM)成像的染色剂。
M55338 Safflower Yellow Safflower yellow 是从植物红花 (Carthamus tinctorius) 的花中提取的,可用于心脑血管疾病的相关研究。红花黄色素主要活性成分为羟基红花黄色素A(HSYA),具有活血通经、化瘀止痛的效用。
M55337 (S)-Mephenytoin (S)-Mephenytoin 是细胞色素 P450 (CYP) 同种型 CYP2C19 的底物。(S)-Mephenytoin 可用于分析细胞色素 P450 代谢。
M55336 IL-4-inhibitor-1 IL-4-inhibitor-1 是第一个 IL-4 的小分子抑制剂,其 EC50 值为 1.81 µM。IL-4-inhibitor-1 对细胞因子具有微摩尔亲和力和效力,可破坏细胞中的 II 型 IL-4 信号传导。
M55335 Coppersensor 1 Coppersensor-1 是一种膜透性荧光染料。Coppersensor-1 对 Cu+ 具有亲和力,其亲和力在皮摩尔范围,对竞争细胞金属离子具有很高的选择性。Coppersensor-1 作为探针,可以选择性、灵敏地检测包括活细胞在内的生物样品中的铜离子 (Cu+)。
M55334 Tanshinol B Tanshinol B (丹参醇 B) 是丹参的一种生物活性成分,能从普氏海草根和根茎的 50% 乙醇提取物中分离得到。
M55333 Recombinant Mouse GDF15 (Mammalian, N-8His-Flag) Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development.
M55332 N-Chlorosuccinimide N-Chlorosuccinimide (琥珀酰基氯亚胺) 是一种氯化和氧化剂。与其他氯化剂(例如1-溴-3-氯-5,5-二甲基乙内酰脲(NDDH)和三氯异氰尿酸(TCCA))相比,这种成分具有更高的区域选择性,因此更有效。
M55331 ICG-amine ICG-amine (ICG-NH2) 是一种近红外荧光探针,可与氨基酸残基结合,无需冷凝剂。
M55330 Sodium chloride Sodium chloride 是一种无机盐,作为生化试剂,可用于细胞培养,动物实验溶液配置等生物学研究。氯化钠还可用作酸碱平衡调节剂、盐析剂及片剂、胶囊剂的稀释剂等。
M55329 tert-Butyl 3-hydroxypropionate 3-羟基丙酸叔丁酯 (3-hydroxypropionate;3-HPA) 是合成 wortmannilactone C 的关键起始原料。3-羟基丙酸叔丁酯 (3-hydroxypropionate;3-HPA) 也可用于制备三维金属富勒烯框架 (MFF)。
M55328 3-Hydroxypropionic acid sodium salt 3-Hydroxypropionic acid sodium salt 是一种合成多种工业用化合物的基础砌块。3-Hydroxypropionic acid sodium salt 可用于合成一些可降解塑料和生产一系列 C3 化合物。
M55327 Recombinant Mouse CX3CL1 Protein (Mammalian, C-6His) C-X3-C motif Chemokine 1 (CX3CL1; Fractalkine) is a single-pass type I membrane protein which belongs to the intercrine delta family. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.
M55326 JG-2016 JG-2016 是一种有效的组蛋白乙酰转移酶 1 (HAT1) 抑制剂,在 HAT1 乙酰化检测中 IC50 为 14.8 μM。
M55325 Recombinant Human IL-29/IFN-λ1 (Mammalian, C-10His) Interleukin-29 (IL-29; IFN-λ1) is a cytokine with immunomodulatory activity. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity.
M55324 N-Oxalylglycine N-Oxalyglycine (N-Oxaloglycine) 是一种广谱 2-氧化戊二酸加氧酶 (2-oxoglutarate oxygenase) 抑制剂。
M55323 JBH492 JBH492 是一种首创 (first-in-class) 的(C-C 趋化因子受体 7)CCR7 靶向 ADC,由人源化、Fc 稀释的抗 CCR7 IgG1 抗体通过可裂解连接体与 maytansinoid 微管抑制剂 DM4 连接组成。
M55322 LY3471851 LY3471851 (Rezpegaldesleukin, NKTR-358) 是一种潜在“first-in-class”调节性 T 细胞(Treg)诱导 IL-2 结合物,它靶向体内的白介素2(IL-2)受体复合物,可以刺激抑制性免疫细胞调节性T 细胞(Treg)增殖。
M55321 Filanesib hydrochloride Filanesib (ARRY-520) hydrochloride 是一种选择性和非竞争性 纺锤体驱动蛋白 (KSP) 抑制剂,对人类 KSP 的 IC50 值为 6 nM。Filanesib 在体外诱导细胞凋亡 (apoptosis)。
M55320 MP7 MP7 (PDK1 inhibitor) 是一种磷酸肌醇依赖性激酶-1 (PDK1) 抑制剂。
M55319 Saccharin sodium Saccharin sodium 是一种甜味剂。
M55318 Dulcin Dulcin (DL), 4-ethoxyphenylurea, a synthetic chemical about 200 times as sweet as sucrose, has been proposed for use as an artificial sweetener.
M55317 IA9 TFA IA9 TFA 是一种 TREM-2 抑制剂,IA9 TFA 可减少胶原诱导关节炎小鼠促炎因子的释放,显著抑制关节炎症和损伤。
M55316 SPD-473 citrate SPD-473 citrate 是一种5-HT(血清素)/多巴胺/去甲肾上腺素再摄取抑制剂。SPD-473 可抑制多巴胺、5-HT(5-羟色胺, 血清素)和去甲肾上腺素的再摄取,是一种可用于帕金森研究的三重再摄取抑制剂。
M55315 Demethylcantharidate disodium Demethylcantharidate disodium 是一种内源性代谢产物,通过内质网应激诱导肝癌细胞凋亡。Demethylcantharidate disodium 具有良好的抗癌活性。
M55314 Recombinant Mouse Decorin Protein (Mammalian, C-6His) Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.
M55313 Recombinant Human Decorin Protein (HEK293) Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.
M55312 Recombinant Human Decorin Protein (Mammalian, C-6His) Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.
M55311 Mitoguazone Mitoguazone 是一种可透过血脑屏障的竞争性的 S-腺苷-蛋氨酸脱羧酶 (S-adenosyl-methionine decarboxylase) 抑制剂,可破坏多胺的生物合成。Mitoguazone 诱导细胞凋亡 (apoptosis),可抑制 HIV DNA 整合到单核细胞和巨噬细胞中的细胞 DNA 中。
M55310 BI 1291583 BI 1291583是一种新型的组织蛋白酶C (cathepsin C; CatC; DPP1) 选择性抑制剂。BI 1291583以共价、可逆的方式结合人DPP-1并高效抑制DPP-1活性。
M55309 Total flavonoids from Astragali radix 黄芪总黄酮是从黄芪中分离的主要活性成分,具有抗氧化,清除自由基,抗损伤、抗突变、抗肿瘤和抑制动脉粥样硬化等多种生物学效应。
M55308 ARTS-021 ARTS-021是一款潜在同类最佳的、可逆的、口服选择性的 细胞周期蛋白依赖性激酶2(CDK2)抑制剂,以纳摩尔效力抑制 CDK2,比对 CDK1 的选择性超过 600 倍。
M55307 Recombinant Human TIM-4 Protein (Mammalian, C-6His) T-cell Immunoglobulin and Mucin Domain-containing Protein 4(TIM-4) belongs to the immunoglobulin superfamily. TIM-4 is expressed by macrophages and mature dendritic cells but not by lymphocytes. it is Involved in regulating T-cell proliferation and lymphotoxin signaling.
M55306 Guanosine 3′,5′-cyclic monophosphate Guanosine 3′,5′-cyclic monophosphate (cGMP, 鸟苷 3',5'-环单磷酸) 作为一种重要的第二信使,cGMP 是细胞外信号(如一氧化氮和利钠肽)的主要细胞内介质。cGMP 与三种类型的细胞内受体蛋白相互作用:cGMP 依赖性蛋白激酶、cGMP 调节的通道和 cGMP 调节的环核苷酸磷酸二酯酶。体内 cGMP 水平升高的主要作用是刺激 cGMP 依赖性蛋白激酶 (PKG)。
M55305 HJC0123 HJC0123 是一种新型 STAT3 抑制剂,可抑制造血干细胞的纤维化特性。HJC0123 可降低 STAT3 的磷酸化、核转位和转录活性。在亚摩尔浓度下,HJC0123能抑制造血干细胞的增殖。它降低了 STAT3 调控蛋白的表达,诱导细胞周期停滞,促进细胞凋亡,并下调 SOCS3。
M55304 ODZ10117 ODZ10117 是一种 STAT3 小分子抑制剂。ODZ10117 通过靶向 STAT3 抑制胶质母细胞瘤细胞的迁移和侵袭,并诱导细胞凋亡。
M55303 Clopyralid Clopyralid 对杂草施用后,被植物的叶片或根部吸收,然后在植物体内进行传导,引起细胞分裂失控和无序生长,最后导致维管束被破坏,也能够抑制细胞的分裂和生长。
M55302 Myosin H Chain Fragment, mouse acetate Myosin H Chain Fragment, mouse acetate salt 是源于 α-肌球蛋白重链肽的一个肽段,可以用来诱导实验性自身免疫性心肌炎 (EAM) 小鼠模型。
M55301 Myosin H Chain Fragment, mouse Myosin H Chain Fragment, mouse 是源于 α-肌球蛋白重链肽的一个肽段,可以用来诱导实验性自身免疫性心肌炎 (EAM) 小鼠模型。
M55300 Menaquinone-7 维生素k2(MK-7,Menaquinone-7)是一种具有口服活性的维生素 K2 家族的成员,最早作为抗出血因子被发现。维生素K2(甲萘醌-7)存在于发酵食品和动物制品中,也由肠道细菌产生,是一种脂溶性维生素,也是人体不可缺少的重要维生素之一。维生素K2能够激活多种维生素K依赖蛋白,在心血管和骨骼健康中发挥着关键作用。
M55299 Recombinant Human FLT3L (Mammalian, C-6His) Fms-like Tyrosine Kinase 3 Ligand (FLT3L,FMS样胰激酶3配体) is a hematopoietic four helical bundle cytokine. Flt‑3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.









021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号