| 目录号 | 产品名称 | 产品简介 |
|---|---|---|
M21466
|
Recombinant Rat TNF-α (P. pastoris) | 重组大鼠肿瘤坏死因子α（rrTNF-α）在生长调节、分化、炎症、病毒复制、肿瘤发生和自身免疫性疾病中发挥着重要作用。ED50 < 50.0 pg/ml |
| M21094
|
Recombinant Rat IL-1β (E. coli) | 白细胞介素-1β（IL-1β）是一种非分泌的促炎症细胞因子，主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定，ED50为 < 10.0 pg/ml，相当于比活性 > 1.0 × 108 units/mg。 |
| M19999
|
Recombinant Mouse IL-2 (E.coli) | Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells. |
| M10922
|
Recombinant Mouse TGF-beta 1 Protein (Human Cells) | 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子，其控制许多生物过程，包括免疫，分化，肿瘤抑制，肿瘤转移，衰老，迁移，伤口愈合，细胞凋亡，细胞分裂，脂肪生成和成骨。ED50为5-25 pg/ml |
| M10465
|
Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) | Recombinant Mouse Interleukin-4是一种多效性细胞因子，可调节多种T和B细胞反应，包括细胞增殖、存活和基因表达。IL-4 调节天然 CD4+ T 细胞（Th0 细胞）向辅助 Th2 细胞的分化，并调节免疫球蛋白类别转换为 IgG1 和 IgE 同种型。 |
| M10022
|
Recombinant Mouse GM-CSF Protein (CHO) | 重组小鼠GM-CSF蛋白是一种生长因子，可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生，包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml，对应于>2.0 × 107units/mg的比活性。 |
| M9987
|
Recombinant Human PDGF-AA Protein (HEK293) | 重组人PDGF-AA蛋白（Recombinant Human PDGF-AA Protein）是一种有效的促细胞分裂剂，适用于多种细胞类型，包括平滑肌细胞，结缔组织细胞，骨骼和软骨细胞以及一些血细胞。 |
| M9981
|
Recombinant Human IL-11 Protein (E. coli) | 重组人IL-11蛋白（Recombinant Human IL-11 Protein）是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。 |
| M9413
|
Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。 |
| M9406
|
Recombinant Human bFGF Protein (HEK293) | 重组人碱性成纤维细胞生长因子（bFGF）是成纤维细胞生长因子家族的一个成员，能够刺激中胚层来源的细胞、神经外胚层，外胚层和内胚层来源细胞的增殖。 |
| M9402
|
Recombinant Human PDGF-BB Protein (HEK293, C-His) | PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体，分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原，包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。 |
| M9391
|
Recombinant Human TGF-β1 (CHO) | 重组人TGF-β1（Recombinant Human TGF-β1）是一种多功能细胞因子，调节细胞增殖、生长、分化和运动，以及细胞外基质的合成和沉积。 |
| M9370
|
Recombinant Human TNF α (HEK293, C-His) | 重组人肿瘤坏死因子α（Recombinant Human TNF α）是一个同源三聚体，它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。 |
| M9241
|
Recombinant Human EPO Protein (CHO) | 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子，主要以其在促红细胞生成中的作用而闻名，它负责刺激红系祖细胞的增殖和分化。 |
M58135
|
Recombinant Human DEFB3 (E. coli) | Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
| M58127
|
Recombinant Human Progranulin Protein (HEK293, C-His) | Progranulin is also called Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. |
| M58115
|
Recombinant Human Bcl-2 Protein (E. coli, C-His) | B-cell leukemia/lymphoma 2, also known as Bcl-2, belongs to the Bcl-2 family. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor. |
| M58110
|
Recombinant Human RIPK3 Protein (E. coli, N-His) | RIPK3 是一种控制坏死性凋亡和细胞凋亡的激酶。在坏死性凋亡中，由 TNF-α 和 ZBP1 激活，RIPK3 磷酸化 MLKL，导致膜损伤。 |
| M58101
|
Recombinant Human EGFR Protein (CHO, C-His) | EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. |
| M57289
|
Recombinant Human ITGB1 (Mammalian, C-6His) | Integrin β-1 (ITGB1) belongs to the integrin β chain family. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
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