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Recombinant Human FGF-basic (145aa, E. coli) 重组人FGF basic/bFGF蛋白 (145aa, E. coli)

目录号 M11108 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人FGF basic/bFGF 蛋白 (145aa, E. coli) 也称为 FGF-2,是一种多效细胞因子,是肝素结合 FGF 家族的原型成员之一。

Recombinant Human FGF-basic (145aa, E. coli)结构式

别名:Fibroblast Growth Factor-basic; FGF-2

规格 价格 库存状态
10ug ¥ 1200 中国库存现货
50ug ¥ 2200 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

重组人FGF basic/bFGF 蛋白 (145aa, E. coli) 也称为 FGF-2,是一种多效细胞因子,是肝素结合 FGF 家族的原型成员之一。FGF-basic 具有 β 三叶结构。在体内,碱性 FGF 由多种细胞产生,包括心肌细胞、成纤维细胞和血管细胞。FGF-basic 调节多种过程,包括细胞增殖、分化、存活、粘附、运动、细胞凋亡、肢体形成和伤口愈合。FGF-basic 由于其在血管生成和血管重塑中的作用而可能是致瘤性的。FGF-basic 的血管生成作用可在急性心脏损伤期间产生有益的心脏保护作用。

Measured by the cell proliferation assay using 3T3 cells, the ED50 is < 0.25 ng/ml, corresponding to a specific activity of > 4.0 × 106 units/mg.


Accession: P09038

Apparent Molecular Weight: ~16.4 kDa, reducing conditions.

Lyophilized after extensive dialysis against PBS.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml
储存条件 Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Xiaochen Chen, et al. Int J Environ Res Public Health. Plasma Inflammatory Biomarkers Associated with Advanced Liver Fibrosis in HIV-HCV-Coinfected Individuals

[2] Xiang Lin, et al. Redox Biol. Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility

[3] M Klagsbrun. Prog Growth Factor Res. The fibroblast growth factor family: structural and biological properties

[4] J W Moore, et al. Development. The mRNAs encoding acidic FGF, basic FGF and FGF receptor are coordinately downregulated during myogenic differentiation

[5] D Ledoux, et al. Prog Growth Factor Res. Interactions of FGFs with target cells

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