—更好的抑制剂,金标准的化合物库
致电  021-50967598
在线客服

Stem Cells & Wnt

查阅相关靶点产品

Stem Cells & Wnt信号通路图概览

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell. Specifically, the JAK/STAT, Hedgehog, Wnt, Notch, Smad, PI3K/phosphatase and tensin homolog, and NK-κB signaling pathways have all been shown experimentally to mediate various stem cell properties, such as self-renewal, cell fate decisions, survival, proliferation, and differentiation. Cancer stem cells (CSCs) have been believed to be responsible for tumor initiation, growth, and recurrence. Numerous agents have been developed to specifically target CSCs by suppressing the expression of pluripotency maintaining factors Nanog, Oct-4, Sox-2, and c-Myc and transcription of GLI. Induced pluripotent stem cells (iPSCs) have the capacity to differentiate into various types of cells, and a self-renewing resource, and scientists can experiment with an unlimited number of pluripotent cells to perfect the process of targeted differentiation, transplantation, and more, for personalized medicine.











021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号