Recombinant Human BMP-4 Protein (E. coli) 别名：Bone morphogenetic protein 4; 重组人BMP-4蛋白 (E. coli)
BMP-4 is involved in the development and maintenance of bone and cartilage. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells.
J Gastroenterol Hepatol. 2025 Mar 26.
化学性质/溶解性/储存
| 性状 | Lyophilized powder |
| 中文名称 | 重组人BMP-4蛋白 (E. coli) |
| 溶解性 | Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. |
| 储存条件 | Stable for up to 12 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
生物活性
BMP-4 is involved in the development and maintenance of bone and cartilage. Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells.
Accession: P12644
Molecular Weight: ~13.3 kDa
Endotoxin < 0.2 EU/μg
Lyophilized from a 0.2 μm filtered solution in 50 mM Na2CO3, 5 mM DTT, pH 11.0.
实验参考
建议您制定动物给药及实验方案时，尽量参考已发表的相关实验文献（溶剂种类及配比众多，简单地溶解目的化合物，并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题，未必能保证目的化合物在动物体内充分发挥生物学效用）。
体内实验的工作液，建议您现用现配，当天使用；如在配制过程中出现沉淀、析出现象，可以通过超声和（或）加热的方式助溶。
切勿一次性将产品全部溶解。
请在下面的计算器中，输入您的动物实验相关数据并点击计算，即可得到该实验的总需药量和工作液终浓度。
例如您给药剂量是10 mg/kg，平均每只动物的体重为20 g，每只动物的给药体积是100 μL，动物数量为20只，则该动物实验的总需药量为4 mg，工作液终浓度为2 mg/mL。
1：鉴于实验过程的损耗，建议您至少多配1-2只动物的量；
2：为该产品最终给药时的浓度。
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参考文献
