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Recombinant Proteins 重组蛋白/细胞因子/生长因子 Recombinant Proteins

目录号 产品名称 产品简介
M9370 Recombinant Human TNF α (HEK293, C-His) 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml
M9391 Recombinant Human TGF-β1 (HEK293, C-Fc) 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。通过抑制 IL-4 依赖性的小鼠 HT-2 细胞的增殖能力来测定的ED50值为 ≤0.5 ng/mL。
M9241 Recombinant Human EPO Protein (HEK293, C-His) 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。
M9987 Recombinant Human PDGF-AA Protein (HEK293) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M9981 Recombinant Human IL-11 Protein (HEK293) 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。
M21094 Recombinant Rat IL-1β (E. coli) 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
M10022 Recombinant Mouse GM-CSF Protein (CHO) 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。
M45269 Recombinant Mouse Fas Ligand Protein (Yeast, His Tag) Fas Ligand is the ligand for FAS, it is a transmembrane protein which binds to TNFRSF6/FAS. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development.
M45265 Recombinant Mouse PD-1 Protein (Mammalian, C-Fc) Programmed Death-1 (PD-1) is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and acts as an important immunosuppressive molecule.
M45205 Recombinant Mouse IL-11 (HEK 293) Interleukin-11 (IL-11) is a pleiotropic cytokine that has multiple effects on both hematopoietic and nonhematopoietic cells.
M45176 Recombinant Human B7-H3/CD276 Protein (Mammalian, C-6His) B7-H3 (also known as CD276) is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is involved in the activation of T lymphocytes, and regulates murine bone formation.
M45127 Recombinant Human ANXA2 Protein (E. coli) Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways.
M45121 Recombinant Human IL-17B (Mammalian, C-Fc) Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases.
M45112 Recombinant Human GOLM1 Protein(C-6His) 重组人GOLM1蛋白(C-6His)属于 GOLM1/CASC4 家族,GOLM1 是一种单通道 II 型膜蛋白,可在许多组织中发现,并在前列腺癌和肺腺癌组织中过表达。此外,GOLM1 由 E1A 腺病毒蛋白诱导,在病毒感染时上调,在内质网输出蛋白质的分拣和修饰过程中发挥着关键作用。
M45089 Recombinant Human Granzyme B Protein (HEK293, C-His) Granzyme B is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells.
M45088 Recombinant Human COX-2 Protein (Baculovirus-Insect, C-His) COX-2 is s component of Prostaglandin-endoperoxide synthase (PTGS). It is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase.
M45068 Recombinant Human HDAC8 Protein (GST Tag) Histone deacetylase 8(HDAC8,HDACL1)是一种细胞核和细胞质蛋白质,属于组蛋白去乙酰化酶家族和 HD 1 型亚族,能通过影响细胞核中核心组蛋白的乙酰化状态参与转录调控。HDAC8 / HDACL1 在大多数组织中表达较弱,在心脏、大脑、肾脏和胰腺以及肝脏、肺脏、胎盘、前列腺和肾脏中的表达水平较高。HDAC8 / HDACL1 负责核心组蛋白(H2A、H2B、H3 和 H4)N 端赖氨酸残基的去乙酰化。
M45059 Recombinant Human uPA (Mammalian, C-6His) Recombinant Human Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium.
M45057 Recombinant Human IDO Protein (E.coli, N-6His) Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway.
M45052 Recombinant Human IL-7 (Mammalian, C-6His) Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor.
M45051 Recombinant Human IL-7 (E. coli) Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor.
M43971 Recombinant Human MMP12 Protein (E. coli) Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect.
M43970 Recombinant Human MMP-8 Protein (HEK293, C-His) Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development.
M43969 Recombinant Mouse MMP-12 (Mammalian, C-6His) Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity.
M43966 Recombinant Human IL-1β Protein (E.coli) 重组人白介素 1β(Recombinant Human IL-1β)是一种在多种细胞中产生的促炎细胞因子,包括单核细胞、组织巨噬细胞、角质形成细胞和其他上皮细胞。
M43961 Recombinant Human Claudin-6/CLDN6 Full Length Protein (HEK293, VLP) Claudin-6 (CLDN6) belongs to the claudins family. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function.
M43960 Recombinant Mouse Sclerostin (Mammalian, C-6His) Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation.









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