目录号 | 产品名称 | 产品简介 |
---|---|---|
M9370 | Recombinant Human TNF α (HEK293, C-His) | 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。 |
M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。 |
M10922 | Recombinant Mouse TGF-beta 1 Protein (Human Cells) | 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml |
M9391 | Recombinant Human TGF-β1 (HEK293, C-Fc) | 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。通过抑制 IL-4 依赖性的小鼠 HT-2 细胞的增殖能力来测定的ED50值为 ≤0.5 ng/mL。 |
M9241 | Recombinant Human EPO Protein (HEK293, C-His) | 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。 |
M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。 |
M9987 | Recombinant Human PDGF-AA Protein (HEK293) | 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。 |
M9981 | Recombinant Human IL-11 Protein (HEK293) | 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。 |
M21094 | Recombinant Rat IL-1β (E. coli) | 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。 |
M10022 | Recombinant Mouse GM-CSF Protein (CHO) | 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。 |
M45269 | Recombinant Mouse Fas Ligand Protein (Yeast, His Tag) | Fas Ligand is the ligand for FAS, it is a transmembrane protein which binds to TNFRSF6/FAS. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. |
M45265 | Recombinant Mouse PD-1 Protein (Mammalian, C-Fc) | Programmed Death-1 (PD-1) is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and acts as an important immunosuppressive molecule. |
M45205 | Recombinant Mouse IL-11 (HEK 293) | Interleukin-11 (IL-11) is a pleiotropic cytokine that has multiple effects on both hematopoietic and nonhematopoietic cells. |
M45176 | Recombinant Human B7-H3/CD276 Protein (Mammalian, C-6His) | B7-H3 (also known as CD276) is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is involved in the activation of T lymphocytes, and regulates murine bone formation. |
M45127 | Recombinant Human ANXA2 Protein (E. coli) | Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. |
M45121 | Recombinant Human IL-17B (Mammalian, C-Fc) | Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. |
M45112 | Recombinant Human GOLM1 Protein(C-6His) | 重组人GOLM1蛋白(C-6His)属于 GOLM1/CASC4 家族,GOLM1 是一种单通道 II 型膜蛋白,可在许多组织中发现,并在前列腺癌和肺腺癌组织中过表达。此外,GOLM1 由 E1A 腺病毒蛋白诱导,在病毒感染时上调,在内质网输出蛋白质的分拣和修饰过程中发挥着关键作用。 |
M45089 | Recombinant Human Granzyme B Protein (HEK293, C-His) | Granzyme B is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. |
M45088 | Recombinant Human COX-2 Protein (Baculovirus-Insect, C-His) | COX-2 is s component of Prostaglandin-endoperoxide synthase (PTGS). It is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. |
M45068 | Recombinant Human HDAC8 Protein (GST Tag) | Histone deacetylase 8(HDAC8,HDACL1)是一种细胞核和细胞质蛋白质,属于组蛋白去乙酰化酶家族和 HD 1 型亚族,能通过影响细胞核中核心组蛋白的乙酰化状态参与转录调控。HDAC8 / HDACL1 在大多数组织中表达较弱,在心脏、大脑、肾脏和胰腺以及肝脏、肺脏、胎盘、前列腺和肾脏中的表达水平较高。HDAC8 / HDACL1 负责核心组蛋白(H2A、H2B、H3 和 H4)N 端赖氨酸残基的去乙酰化。 |
M45059 | Recombinant Human uPA (Mammalian, C-6His) | Recombinant Human Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. |
M45057 | Recombinant Human IDO Protein (E.coli, N-6His) | Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. |
M45052 | Recombinant Human IL-7 (Mammalian, C-6His) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. |
M45051 | Recombinant Human IL-7 (E. coli) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. |
M43971 | Recombinant Human MMP12 Protein (E. coli) | Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. |
M43970 | Recombinant Human MMP-8 Protein (HEK293, C-His) | Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development. |
M43969 | Recombinant Mouse MMP-12 (Mammalian, C-6His) | Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. |
M43966 | Recombinant Human IL-1β Protein (E.coli) | 重组人白介素 1β(Recombinant Human IL-1β)是一种在多种细胞中产生的促炎细胞因子,包括单核细胞、组织巨噬细胞、角质形成细胞和其他上皮细胞。 |
M43961 | Recombinant Human Claudin-6/CLDN6 Full Length Protein (HEK293, VLP) | Claudin-6 (CLDN6) belongs to the claudins family. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. |
M43960 | Recombinant Mouse Sclerostin (Mammalian, C-6His) | Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation. |
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