Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。
Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子。VEGF 促进内皮细胞的增殖和存活，促进血管生成和血管通透性。VEGF 在血管化组织中表达，在正常和病理血管生成中起着重要作用。大量证据表明 VEGF 在诱导肿瘤转移和眼内新生血管综合征中有重要作用。VEGF 通过 FMS-like 酪氨酸激酶(Flt-1)、KDR 基因产物(小鼠同源性为 FLK--1 基因产物)和 FLT 4 基因产物表达。
DNA 序列编码人 VEGF165（NP_001165097.1）表达带有 His 标签在 C 末端。
重组人 VEGF165 包含 193 个氨基酸，预测的理论分子量为 22.3kd。
通过用人脐静脉内皮细胞(HUVEC)进行细胞增殖测定，该效应的ED50为≤20 ng/mL。
Endotoxin <0.1EU/μg
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USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma
Sci Rep. 2019 Nov 28;9(1):17745.
In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
| 其他相关的Recombinant Proteins产品 |
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| Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
| Recombinant Human EpCAM/Trop-1 (Mammalian, C-Fc)
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein. EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells. |
| Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli, aa 18-169, His Tag)
The recombinant human IL1F9 consists of 168 amino acids and predicts a molecular mass of 19.1 KDa. A DNA sequence encoding the mature form of human IL1F9 (Ser18-Asp169) was expressed with a polyhistide tag at the N-terminus. |
| Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli)
The recombinant human IL1F9 consisting of 169 amino acids and has a calculated molecular mass of 18.9 kDa. A DNA sequence encoding the human IL-1F9 isoform 1 (Met 1-Asp 169) was expressed. |
| Recombinant Human APOL1 Protein (Baculovirus-Insect, C-His)
APOL1, also known as apolipoprotein L1, belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. |
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