M9370
|
Recombinant Human TNF α (HEK293, C-His) |
重组人肿瘤坏死因子α（Recombinant Human TNF α）是一个同源三聚体，它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。 |
| M9413
|
Recombinant Human VEGF165 Protein (HEK293, C-His) |
Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。 |
| M10922
|
Recombinant Mouse TGF-beta 1 Protein (Human Cells) |
重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子，其控制许多生物过程，包括免疫，分化，肿瘤抑制，肿瘤转移，衰老，迁移，伤口愈合，细胞凋亡，细胞分裂，脂肪生成和成骨。ED50为5-25 pg/ml |
| M9391
|
Recombinant Human TGF-β1 (CHO) |
重组人TGF-β1（Recombinant Human TGF-β1）是一种多功能细胞因子，调节细胞增殖、生长、分化和运动，以及细胞外基质的合成和沉积。 |
| M9241
|
Recombinant Human EPO Protein (CHO) |
促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子，主要以其在促红细胞生成中的作用而闻名，它负责刺激红系祖细胞的增殖和分化。 |
| M9402
|
Recombinant Human PDGF-BB Protein (HEK293, C-His) |
PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体，分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原，包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。 |
| M9987
|
Recombinant Human PDGF-AA Protein (HEK293) |
重组人PDGF-AA蛋白（Recombinant Human PDGF-AA Protein）是一种有效的促细胞分裂剂，适用于多种细胞类型，包括平滑肌细胞，结缔组织细胞，骨骼和软骨细胞以及一些血细胞。 |
| M9981
|
Recombinant Human IL-11 Protein (E. coli) |
重组人IL-11蛋白（Recombinant Human IL-11 Protein）是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。 |
| M21094
|
Recombinant Rat IL-1β (E. coli) |
白细胞介素-1β（IL-1β）是一种非分泌的促炎症细胞因子，主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定，ED50为 < 10.0 pg/ml，相当于比活性 > 1.0 × 108 units/mg。 |
| M10022
|
Recombinant Mouse GM-CSF Protein (CHO) |
重组小鼠GM-CSF蛋白是一种生长因子，可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生，包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml，对应于>2.0 × 107units/mg的比活性。 |
M9363
|
Recombinant Human IL-4 Protein (CHO, C-Fc) |
重组人白介素4（Recombinant Human IL-4）在由单核细胞诱导成DC的过程中抑制巨噬细胞的过度生长，从而引导单核细胞向DC方向分化。 |
| M9362
|
Recombinant Human IL-2 (CHO-expressed) High Efficiency |
重组人白介素2（Recombinant Human IL-2）可以使活化的T细胞在体外培养中长期持续增殖。 |
| M9361
|
Recombinant Human IL-1α Protein (E. coli) |
白细胞介素-1α（IL-1α）又称 IL1F1，属于由 IL1A 基因编码的 IL-1 家族的细胞因子，是分子量为 31kD 的前体蛋白。IL-1α既可作为分泌型细胞因子，又可作为 IL-1 家族中仅有的膜结合型细胞因子。IL-1α在功能上控制细胞增殖、分化和凋亡并广泛应用于造血活性、免疫应答和炎症反应的研究。 |
| M9344
|
Recombinant Human GM-CSF (HEK293, C-His) |
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor 是一种造血生长因子和免疫调节剂。GM-CSF 在体外可刺激中性粒细胞和巨噬细胞的集落形成，并具有促进早期红巨核细胞、嗜酸性祖细胞增殖和发育功能。GM-CSF在DC培养中的功能是促进单核细胞向大巨噬样细胞分化，细胞表面 MHC II 类分子的表达得以提高，从而增强细胞的抗原递呈功能。 |
| M9240
|
Recombinant Human IFNγ (CHO) |
Human Interferon gamma (hIFN-γ) 重组人干扰素γ主要是由抗原、有丝分裂原或同种抗原激活的 T 细胞和自然杀伤细胞产生的，具有较强的免疫调节功能， |
| M5726
|
Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His) |
Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
| M58536
|
Recombinant Mouse CD5L Protein (HEK293, C-6His) |
CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily. CD5L regulates mechanisms in inflammatory responses, such as infection or atherosclerosis. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. |
| M58535
|
Recombinant Human CD5L Protein (HEK293, C-6His) |
CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily. CD5L regulates mechanisms in inflammatory responses, such as infection or atherosclerosis. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. |
| M58321
|
Recombinant Human Complement C3 (E. coli) |
Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. |
| M58128
|
Recombinant Human MIA Protein (E.coli, C-6His) |
黑色素瘤抑制活性 (MIA) 蛋白在体外对黑色素瘤细胞表现出显著的生长抑制作用，并且对各种神经外胚层肿瘤（例如神经胶质瘤）也显示出类似的作用。MIA 引起生长抑制的能力表明其作为肿瘤抑制因子的潜在作用，特别是在源自神经外胚层组织的恶性肿瘤的情况下。此外，MIA 与 FASLG 相互作用，表明它参与与细胞凋亡和免疫反应相关的细胞过程。 |
| M54854
|
Sotatercept-csrk |
Sotatercept-csrk 是第一个获得FDA批准的激活素信号抑制剂，它通过改善促增殖和抗增殖信号传导之间的平衡来调节PAH的血管细胞增殖。Sotatercept是一种靶向ACVR2A的融合蛋白，可恢复肺动脉内生长途径的平衡。 |
| M49922
|
Recombinant Human VCAM-1 Protein (HEK293, C-Fc) |
VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. |
| M45267
|
Recombinant Mouse Fas/CD95 Protein (HEK293, C-6His) |
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
| M45264
|
Recombinant Mouse PD-1 Protein (HEK293, C-6His) |
Programmed Death-1 (PD-1) is one member of CD28/CTLA-4 superfamily. PD-1 belongs to type I transmembrane protein and acts as an important immunosuppressive molecule. |
| M45091
|
Recombinant Mouse Apolipoprotein E (HEK293, C-6His) |
Apolipoprotein E (Apo-E) is a member of the apolipoprotein A1/A4/E family. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. |
| M40901
|
Recombinant Human LBP (HEK293, C-6His) |
Lipopolysaccharide binding protein (LBP) is a plasma protein, it is involved in the acute-phase immunologic response to gram-negative bacterial infections. |
| M31134
|
Recombinant Mouse Prolactin/PRL Protein (HEK293, C-6His) |
Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation. |
| M10009
|
Recombinant Human Apo-transferrin Protein |
Transferrin is iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. |
| M10007
|
Recombinant Human Holo-Transferrin Protein |
Transferrin是一种与铁结合的血浆糖蛋白，可控制生物体中游离铁的含量。 |
