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Recombinant Human IL-1α Protein (HEK293) 重组人白介素1α (HEK293)

目录号 M9361 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


白介素 1 (IL-1)是一种多肽,分子质量为17 kd,有IL-1α及IL-1β两种亚型。IL-1ɑ由159个氨基酸组成。

Recombinant Human IL-1α Protein (HEK293)结构式
规格 价格 库存状态
10ug ¥ 2700 中国库存现货
20ug ¥ 4000 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >90%, Endotoxin < 0.1 EU/ug
  • COA
  • MSDS
生物活性

白介素 1 (IL-1)是一种多肽,分子质量为17 kd,有IL-1α及IL-1β两种亚型。IL-1ɑ由159个氨基酸组成。IL-1 受体(IL-1R)几乎存在于所有有核细胞表面,每个细胞的 IL-1R 数目不等,少则几十个(如 t 细胞),多则数千个(如成纤维细胞)。IL-1R 主要有两种类型:一种为 IL-1r1,其分子伸入胞浆内的肽链部分较长,起着传递活化信号的作用;另一种为 IL-1R2,胞内部分的肽段较短不能有效地传递信号,而是将胞外部分的肽链释放到细胞外液中,以游离形式与 IL-1 结合,发挥反馈抑制作用。GM-CSF、G-CSF及 IL-1 自身均可提高细胞 IL-1R 的表达水平,而 TGF 及皮质类固醇能降低 IL-1R 的表达。

通过其诱导人自然杀伤性淋巴瘤 NK-92 细胞分泌干扰素γ 的能力测定,该效应的ED50为 ≤100 ng/mL。

内毒素 <0.1EU/ug

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
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