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Recombinant Rat IL-1β (E. coli) 重组大鼠 IL-1β 蛋白 (E. coli)

目录号 M21094 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。

Recombinant Rat IL-1β (E. coli)结构式

别名:Interleukin-1 Beta; IL1F2

规格 价格 库存状态
10ug ¥ 1850 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。它具有代谢、生理、造血活性,并在免疫反应的调节中发挥核心作用之一。IL-1α和IL-1β都与相同的受体结合,具有相似但不完全相同的生物学特性。成熟的大鼠IL1β与棉鼠和小鼠有90%的相似性,与犬、人和恒河猴的IL1β有65%-77%的相似性。

通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。


Accession # Q63264

Endotoxin < 0.2 EU/μg

Apparent Molecular Weight: ~17.3 kDa, reducing conditions

Lyophilized after extensive dialysis against PBS.

使用AbMole产品发表的文献
化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Boonyalit Throngnumchai, et al. Protein Expr Purif. Refolded recombinant major capsid protein (MCP) from Infectious Spleen and Kidney Necrosis Virus (ISKNV) effectively stimulates serum specific antibody and immune related genes response in Nile tilapia (Oreochromis niloticus)

[2] H R Anforth, et al. Eur Cytokine Netw. Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta

[3] M Zetterstrm, et al. Eur Cytokine Netw. Interleukin-1-mediated febrile responses in mice and interleukin-1 beta activation of NFkappaB in mouse primary astrocytes, involves the interleukin-1 receptor accessory protein

[4] T Takao, et al. Brain Behav Immun. Modulation of interleukin-1 receptors in the brain-endocrine-immune axis by stress and infection

[5] K R Hejnaes, et al. Biol Chem Hoppe Seyler. The effect of N-terminal extension on the structure and function of human interleukin-1 beta

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关键词:Recombinant Rat IL-1β (E. coli), Interleukin-1 Beta; IL1F2, Recombinant Rat IL-1β (E. coli)供应商, Recombinant Proteins抑制剂, 购买Recombinant Rat IL-1β (E. coli), Recombinant Rat IL-1β (E. coli)溶解度, Recombinant Rat IL-1β (E. coli)结构式








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