白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
别名:Interleukin-1 Beta; IL1F2
白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。它具有代谢、生理、造血活性,并在免疫反应的调节中发挥核心作用之一。IL-1α和IL-1β都与相同的受体结合,具有相似但不完全相同的生物学特性。成熟的大鼠IL1β与棉鼠和小鼠有90%的相似性,与犬、人和恒河猴的IL1β有65%-77%的相似性。
通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
Accession # Q63264
Endotoxin < 0.2 EU/μg
Apparent Molecular Weight: ~17.3 kDa, reducing conditions
Lyophilized after extensive dialysis against PBS.
Mol Med Rep. 2023 Nov;28(5):202.
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号