Lipopolysaccharide binding protein (LBP) is a plasma protein, it is involved in the acute-phase immunologic response to gram-negative bacterial infections.
性状 | Lyophilized powder |
中文名称 | 重组人LBP (HEK293, C-6His) |
溶解性 | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
Lipopolysaccharide binding protein (LBP) is a plasma protein, it is involved in the acute-phase immunologic response to gram-negative bacterial infections. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation.
Recombinant Human Lipopolysaccharide-Binding Protein expressed the target gene encoding Ala26-Val481 with a 6His tag at the C-terminus.
Accession: P18428
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 64 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM EDTA, pH 8.0.
建议您制定动物给药及实验方案时,尽量参考已发表的相关实验文献(溶剂种类及配比众多,简单地溶解目的化合物,并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题,未必能保证目的化合物在动物体内充分发挥生物学效用)。
体内实验的工作液,建议您现用现配,当天使用;如在配制过程中出现沉淀、析出现象,可以通过超声和(或)加热的方式助溶。
切勿一次性将产品全部溶解。
请在下面的计算器中,输入您的动物实验相关数据并点击计算,即可得到该实验的总需药量和工作液终浓度。
例如您给药剂量是10 mg/kg,平均每只动物的体重为20 g,每只动物的给药体积是100 μL,动物数量为20只,则该动物实验的总需药量为4 mg,工作液终浓度为2 mg/mL。
1:鉴于实验过程的损耗,建议您至少多配1-2只动物的量;
2:为该产品最终给药时的浓度。