重组人CD48/SLAMF2蛋白 (Mammalian,C-Fc-6His)由哺乳动物表达系统产生,编码Gln27-Ser220的目的基因在c端表达Fc, 6His标签。Accession #: P09326。
别名:CD48 antigen; B-lymphocyte activation marker BLAST-1
纯度:还原SDS-PAGE测定大于95%
内毒素:经LAL测试,小于0.1 ng/ug (1 EU/ug)
存储及稳定性:冻干蛋白应在< -20°C保存,但在室温下可保存3周。重组蛋白溶液可在4-7℃下保存2-7天。重组样品的等分液在< -20°C下稳定3个月
生物活性:CD48抗原,也被称为b淋巴细胞激活标记BLAST-1, BCM1表面抗原,白细胞抗原me -102, TCT.1, CD48, BCM1和BLAST1, CD48含有一个Ig-like C2-type结构域和一个Ig-like V-type结构域,但是没有跨膜结构域,而是通过一个GPI定位点通过一个c端结构域剪切在细胞表面形成可溶性的受体。CD48可能促进活化淋巴细胞之间的相互作用,并参与调节t细胞活化。CD48作为环境传感器在调节祖细胞数量和抑制肿瘤发展方面发挥着重要作用。提示抗cd48单抗有潜力成为治疗多发性骨髓瘤的有效单抗。
分子式 | |
溶解性(25°C) | It is not recommended to reconstitute to a concentration less than 100 μg/ml. |
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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