M9370
|
Recombinant Human TNF α (HEK293, C-His) |
重组人肿瘤坏死因子α（Recombinant Human TNF α）是一个同源三聚体，它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。 |
| M9413
|
Recombinant Human VEGF165 Protein (HEK293, C-His) |
Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。 |
| M10922
|
Recombinant Mouse TGF-beta 1 Protein (Human Cells) |
重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子，其控制许多生物过程，包括免疫，分化，肿瘤抑制，肿瘤转移，衰老，迁移，伤口愈合，细胞凋亡，细胞分裂，脂肪生成和成骨。ED50为5-25 pg/ml |
| M9391
|
Recombinant Human TGF-β1 (CHO) |
重组人TGF-β1（Recombinant Human TGF-β1）是一种多功能细胞因子，调节细胞增殖、生长、分化和运动，以及细胞外基质的合成和沉积。 |
| M9241
|
Recombinant Human EPO Protein (CHO) |
促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子，主要以其在促红细胞生成中的作用而闻名，它负责刺激红系祖细胞的增殖和分化。 |
| M9402
|
Recombinant Human PDGF-BB Protein (HEK293, C-His) |
PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体，分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原，包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。 |
| M9987
|
Recombinant Human PDGF-AA Protein (HEK293) |
重组人PDGF-AA蛋白（Recombinant Human PDGF-AA Protein）是一种有效的促细胞分裂剂，适用于多种细胞类型，包括平滑肌细胞，结缔组织细胞，骨骼和软骨细胞以及一些血细胞。 |
| M9981
|
Recombinant Human IL-11 Protein (E. coli) |
重组人IL-11蛋白（Recombinant Human IL-11 Protein）是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。 |
| M21094
|
Recombinant Rat IL-1β (E. coli) |
白细胞介素-1β（IL-1β）是一种非分泌的促炎症细胞因子，主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定，ED50为 < 10.0 pg/ml，相当于比活性 > 1.0 × 108 units/mg。 |
| M10022
|
Recombinant Mouse GM-CSF Protein (CHO) |
重组小鼠GM-CSF蛋白是一种生长因子，可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生，包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml，对应于>2.0 × 107units/mg的比活性。 |
M55382
|
Recombinant Human IL-25/IL-17E (E. coli, C-His) |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| M55381
|
Recombinant Human IL-25/IL-17E (HEK293, C-6His) |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| M55380
|
Recombinant Human SEMA3A (HEK293, N-6His-Flag) |
Semaphorin 3A (SEMA3A) is a secreted protein which belongs to the semaphorin family. Semaphorin 3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. |
| M55375
|
Recombinant Human CD143/ACE (E. coli, N-GST) |
CD143/ACE Protein is a recombinant human Angiotensin I-converting enzyme (ACE, CD143) which hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity. |
| M55374
|
Recombinant Human Neprilysin (HEK293, N-8His) |
Neprilysin/CD10 (MME; NEP) is a zinc metallopeptidase expressed at the cell surface of a variety of cells. Neprilysin/CD10 (MME) has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide. |
| M55373
|
Recombinant Human THOP1 (E.coli, C-6His) |
Thimet Oligopeptidase (THOP1) is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. |
| M55364
|
Recombinant Mouse IL-22 (HEK293, C-mFc) |
Interleukin-22 (IL-22) is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. |
| M55362
|
Recombinant Human REG4 Protein (HEK293, C-6His) |
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. |
| M55361
|
Recombinant Mouse REG4 Protein (HEK293, His Tag) |
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. |
| M55355
|
Recombinant Mouse IGF-1 (E.coli, C-6His) |
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors. |
| M55353
|
Recombinant Human BMP-9 Protein (E. coli, His Tag) |
Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. |
| M55351
|
Recombinant Human IL-4 Protein (HEK293) |
Interleukin-4 (IL-4) regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. |
| M55350
|
Recombinant Human IL-13 Protein (HEK293, C-Fc) |
Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. |
| M55333
|
Recombinant Mouse GDF15 (HEK293, N-8His-Flag) |
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development. |
| M55327
|
Recombinant Mouse CX3CL1 Protein (HEK293, C-6His) |
C-X3-C motif Chemokine 1 (CX3CL1; Fractalkine) is a single-pass type I membrane protein which belongs to the intercrine delta family. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium. |
| M55325
|
Recombinant Human IL-29/IFN-λ1 (HEK293, C-10His) |
Interleukin-29 (IL-29; IFN-λ1) is a cytokine with immunomodulatory activity. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. |
| M55314
|
Recombinant Mouse Decorin Protein (HEK293, C-6His) |
Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55313
|
Recombinant Human Decorin Protein (HEK293) |
Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55312
|
Recombinant Human Decorin Protein (HEK293, C-6His) |
Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. |
| M55307
|
Recombinant Human TIM-4 Protein (HEK293, C-6His) |
T-cell Immunoglobulin and Mucin Domain-containing Protein 4(TIM-4) belongs to the immunoglobulin superfamily. TIM-4 is expressed by macrophages and mature dendritic cells but not by lymphocytes. it is Involved in regulating T-cell proliferation and lymphotoxin signaling. |
