Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1.
别名:Bone Morphogenetic Protein-9; GDF-2
Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1.
Measure by its ability to induce alkaline phosphatase production by ATDC5 cells, the ED50 for this effect is <0.4 ng/mL.
SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGG
CFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPI
SVLYKDDMGVPTLKYHYEGMSVAECGCR with polyhistidine tag at the N-terminus.
Accession: Q9UK05
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: ~16 KDa, reducing conditions
Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human DEFB3 (E. coli)
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
Recombinant Human MIA Protein (E.coli, C-6His)
黑色素瘤抑制活性 (MIA) 蛋白在体外对黑色素瘤细胞表现出显著的生长抑制作用,并且对各种神经外胚层肿瘤(例如神经胶质瘤)也显示出类似的作用。MIA 引起生长抑制的能力表明其作为肿瘤抑制因子的潜在作用,特别是在源自神经外胚层组织的恶性肿瘤的情况下。此外,MIA 与 FASLG 相互作用,表明它参与与细胞凋亡和免疫反应相关的细胞过程。 |
Recombinant Human Progranulin Protein (HEK293, C-His)
Progranulin is also called Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. |
Recombinant Human Bcl-2 Protein (E. coli, C-His)
B-cell leukemia/lymphoma 2, also known as Bcl-2, belongs to the Bcl-2 family. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor. |
Recombinant Human RIPK3 Protein (E. coli, N-His)
RIPK3 是一种控制坏死性凋亡和细胞凋亡的激酶。在坏死性凋亡中,由 TNF-α 和 ZBP1 激活,RIPK3 磷酸化 MLKL,导致膜损伤。 |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号