Recombinant Human BMP-9 Protein (E. coli, His Tag)  别名:Bone Morphogenetic Protein-9; GDF-2; 重组人BMP-9 蛋白 (E. coli, His Tag)

目录号 M55353

Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1.

Recombinant Human BMP-9 Protein (E. coli, His Tag)结构式

 

规格 价格 库存状态
5ug ¥ 950 现货
本产品不参加促销活动    
*AbMole所有产品仅供有资质的科研机构或医药企业进行科学研究或药证申报用途,不能被用于人体和任何其它用途。我们不向任何个人或非科研性质的机构提供产品和服务。
质量标准及产品资料
  • 纯度:>98%, Endotoxin < 0.01 EU/µg
  • COA
化学性质/溶解性/储存
性状 Lyophilized powder
中文名称 重组人BMP-9 蛋白 (E. coli, His Tag)
溶解性 Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
生物活性

Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1.

Measure by its ability to induce alkaline phosphatase production by ATDC5 cells, the ED50 for this effect is <0.4 ng/mL.

SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGG
CFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPI
SVLYKDDMGVPTLKYHYEGMSVAECGCR with polyhistidine tag at the N-terminus.


Accession: Q9UK05

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: ~16 KDa, reducing conditions

Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.

实验参考
动物实验

建议您制定动物给药及实验方案时,尽量参考已发表的相关实验文献(溶剂种类及配比众多,简单地溶解目的化合物,并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题,未必能保证目的化合物在动物体内充分发挥生物学效用)。
体内实验的工作液,建议您现用现配,当天使用;如在配制过程中出现沉淀、析出现象,可以通过超声和(或)加热的方式助溶。
切勿一次性将产品全部溶解。


动物实验方案计算器

请在下面的计算器中,输入您的动物实验相关数据并点击计算,即可得到该实验的总需药量和工作液终浓度。
例如您给药剂量是10 mg/kg,平均每只动物的体重为20 g,每只动物的给药体积是100 μL,动物数量为20只,则该动物实验的总需药量为4 mg,工作液终浓度为2 mg/mL。

mg/kg
uL
该动物实验的总需药量为 mg
工作液终浓度2 mg/mL

1:鉴于实验过程的损耗,建议您至少多配1-2只动物的量;
2:为该产品最终给药时的浓度。






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