Cytokines and Growth Factors 细胞因子/生长因子 Cytokines and Growth Factors

目录号 产品名称 产品简介
M9370 Recombinant Human TNF α (HEK293, C-His) 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。
M9241 Recombinant Human EPO Protein (CHO) 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。
M9987 Recombinant Human PDGF-AA Protein (HEK293) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M9981 Recombinant Human IL-11 Protein (E. coli) 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。
M21094 Recombinant Rat IL-1β (E. coli) 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
M10022 Recombinant Mouse GM-CSF Protein (CHO) 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。
M54749 Recombinant Rat IL-23 Protein (HEK293, C-His) IL-23 (IL-23 alpha & IL-12 beta Heterodimer) Protein is a recombinant protein dimer complex containing rat-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293.
M54748 Recombinant Rat IL-6 (HEK293) Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses.
M54747 Recombinant Rat IL-12 (HEK293, C-6His) Interleukin 12 (IL-12) has important immunological functions. IL12 facilitates hematopoietic stem cell proliferation, induces NK cell proliferation, and potentiates the expansion and late activation of Th1 CD4+ T cells.
M54745 Recombinant Mouse CTLA-4 Protein (HEK293, C-Flag) Mouse CTLA-4 is a type I transmembrane T cell inhibitory molecule. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal.
M54739 Recombinant Human ICA 512/PTPRN Protein (80AA&94AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54738 Recombinant Human ICA 512/PTPRN Protein (293AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54737 Recombinant Human GAD67 Protein (Baculovirus-Insect, C-His) GAD67 (GAD1) is a member of thegroup II decarboxylase family. GAD67 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker.
M54732 Recombinant Human GAS6 Protein (HEK293, C-6His) GAS6 (Growth arrest-specific protein 6) also known as AXL receptor tyrosine kinase ligand, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest.
M54731 Recombinant Mouse GAS6 Protein (HEK293, C-His) GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells.
M54699 Recombinant Human Lactoferrin/LTF Protein (HEK293, C-6His) Lactoferrin (LTF,乳铁蛋白) 是外分泌液中的主要铁结合蛋白,通过螯合铁和破坏细菌膜而表现出多种抗菌作用。它可以防止生物膜形成,影响骨代谢,并影响腺病毒和乳头瘤病毒感染。
M54637 Recombinant Mouse Thioredoxin/SASP Protein (E. coli) Thioredoxin/SASP 蛋白能参与多种氧化还原反应,并可利用其活性二硫醇中心进行可逆氧化和二硫键形成。它催化重要的二硫醇-二硫化物交换,并在半胱氨酸残基的 S-亚硝基化中发挥关键作用,响应细胞内一氧化氮。
M54636 Recombinant Human Thioredoxin/SASP Protein (E.coli, N-6His) 重组人Thioredoxin/SASP 蛋白能参与多种氧化还原反应,并可利用其活性二硫醇中心进行可逆氧化和二硫键形成。它催化重要的二硫醇-二硫化物交换,并在半胱氨酸残基的 S-亚硝基化中发挥关键作用,响应细胞内一氧化氮。
M54580 Recombinant Human CXCL4/PF-4 Protein (HEK293, C-6His) Human CXCL4/PF-4 is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4/PF-4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair.
M54564 Recombinant Mouse/Rat TGF-beta 2 Protein (HEK293) Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure.
M54561 Recombinant Mouse FABP4 Protein (HEK293, C-His) FABP4 is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family.
M54522 Recombinant Human IFN-α 2b Protein (E. coli) IFN-α 2b (Interferon-Alpha 2b) [Cys24-Glu188 (Lys46Arg)] produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections.
M49940 Recombinant Rat IL-2 (HEK293, C-6His) Interleukin-2 (IL-2) is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
M49920 Recombinant Mouse VCAM-1 Protein (HEK293, C-Fc) Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.
M49919 Recombinant Human VCAM-1 Protein (HEK293, C-6His) VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate.
M49918 Recombinant Mouse GSK-3 beta Protein (Baculovirus-Insect, His Tag) GSK-3 beta/GSK3B Protein is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. GSK3B participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB, and the transcription factor JUN.








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