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Recombinant Mouse Decorin Protein (Mammalian, C-6His) 重组小鼠Decorin 蛋白 (Mammalian, C-6His)

目录号 M55314 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.

Recombinant Mouse Decorin Protein (Mammalian, C-6His)结构式

别名:DCN

规格 价格 库存状态
10ug ¥ 540 中国库存现货
50ug ¥ 1240 中国库存现货
本产品不参加促销活动     其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
生物活性

Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R. DCN suppressed TGF-β1-induced fibrosis by blocking the TGF-β1/SMAD3 signaling pathway.

Recombinant Mouse Decorin expressed the target gene encoding Gly17-Lys354 with a 6His tag at the C-terminus.


Accession: P28654

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 41-50 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
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