重组人BMP-2蛋白 (E.coli) 人骨形态发生蛋白-2 是一种骨生长调节因子,属于转化生长因子-β (TGF-β) 超家族。BMP-2在骨骼和软骨的发育、心肌细胞分化和上皮间充质转化中起重要作用。通过诱导 C2C12 细胞产生碱性磷酸酶的能力来测量,测得的ED50为 0.2-1 µg/ml。
别名:Bone Morphogenetic Protein 2; BMP-2
重组人骨形态发生蛋白-2 (BMP-2) 是一种骨生长调节因子,属于转化生长因子-β (TGF-β) 超家族。重组人BMP-2蛋白在骨骼和软骨的发育、心肌细胞分化和上皮间充质转化中起重要作用。BMP-2还参与hedgehog 信号通路、TGF-β信号通路以及细胞因子-细胞因子受体的相互作用。
通过诱导 C2C12 细胞产生碱性磷酸酶的能力来测量,测得的ED50为 0.2-1 µg/ml。
蛋白编号: # P12643
表观分子量: ~26 kDa,在非还原条件下的 SDS-PAGE 上
剂型描述: 从50mM乙酸的 0.2 μm 过滤溶液中冻干。
溶解性(25°C) | Reconstitute the lyophilized powder in 20 mM AcOH or 5 mM HCl up to 100 μg/ml. |
储存条件 | Stable for up to 6 months at lower than -70°C |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
[4] Branko Skovrlj, et al. Spine (Phila Pa 1976). Association Between BMP-2 and Carcinogenicity
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