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Recombinant Rat TNF-α (P. pastoris) 重组大鼠TNF-α 蛋白 (P. pastoris)

目录号 M21466 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组大鼠肿瘤坏死因子α(rrTNF-α)在生长调节、分化、炎症、病毒复制、肿瘤发生和自身免疫性疾病中发挥着重要作用。ED50 < 50.0 pg/ml

Recombinant Rat TNF-α (P. pastoris)结构式

别名:TNF-alpha; Tumor necrosis factor ligand superfamily member 2

规格 价格 库存状态
10ug ¥ 1395 中国库存现货
50ug ¥ 3960 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

肿瘤坏死因子α(TNF-α)在生长调节、分化、炎症、病毒复制、肿瘤发生和自身免疫性疾病中起主要作用。除诱导肿瘤出血性坏死外,已发现TNF还参与肿瘤发生、肿瘤转移、病毒复制、感染性休克、发烧、炎症和自身免疫性疾病,包括克罗恩病、类风湿性关节炎和移植物抗宿主病。TNFα-1a是一种有效的淋巴因子,对多种肿瘤细胞和某些其他靶细胞产生细胞毒性作用。


Accession #: P06804 

Apparent molecular weight: about 17.4kDa on SDS-PAGE under reduced condition 

Endotoxin: < 0.2 EU/μg 

Lyophilized after extensive dialysis against PBS.

使用AbMole产品发表的文献
化学性质
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml.
储存条件 Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Mingde Ji, et al. PLoS One. C5a Induces the Synthesis of IL-6 and TNF-α in Rat Glomerular Mesangial Cells through MAPK Signaling Pathways

[2] Xu-Hong Wei, et al. Exp Neurol. Peri-sciatic administration of recombinant rat TNF-alpha induces mechanical allodynia via upregulation of TNF-alpha in dorsal root ganglia and in spinal dorsal horn: the role of NF-kappa B pathway

[3] G S Rees, et al. Eur Cytokine Netw. Rat tumour necrosis factor-alpha: expression in recombinant Pichia pastoris, purification, characterization and development of a novel ELISA

[4] A K Olejnik, et al. Immunol Lett. Tumor necrosis factor alpha (TNF-alpha) modulates rat mast cell reactivity

[5] P M Hopkins. Intensive Care Med. Human recombinant TNF alpha affects rat diaphragm muscle in vitro

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