重组人Carboxypeptidase E/CPE蛋白(Mammalian,C-6His)是由哺乳动物表达系统产生的,编码Arg42-Ser453的目的基因在c端以6His标记表达。Accession #: P16870。
别名:Carboxypeptidase H; Enkephalin convertase
纯度:还原SDS-PAGE测定大于95%
内毒素:经LAL测试,小于0.1 ng/ug (1 EU/ug)
存储及稳定性:存放温度≤-70℃,收货后可稳定存放6个月。开封后,在无菌条件下保存3个月,保存温度≤-70℃。请尽量减少冻融循环。
生物活性:CPE的活性形式是切割肽的c端氨基酸残基,因此参与肽激素和胰岛素、脑啡肽等神经递质的生物合成。膜相关的CPE作为一种分选受体,靶向调节的分泌蛋白,主要是垂体的跨高尔基网络和分泌颗粒中的激素前和神经肽进入分泌通路。该蛋白的缺陷与II型糖尿病有关,可导致葡萄糖清除受损和胰岛素抵抗。
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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