—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His) 重组人Carboxypeptidase E/CPE蛋白(Mammalian,C-6His)

目录号 M15008 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人Carboxypeptidase E/CPE蛋白(Mammalian,C-6His)是由哺乳动物表达系统产生的,编码Arg42-Ser453的目的基因在c端以6His标记表达。Accession #: P16870。

Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His)结构式

别名:Carboxypeptidase H; Enkephalin convertase

规格 价格 库存状态
10ug ¥ 2400 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95% , Endotoxin < 1 EU/ug
  • COA
  • MSDS
生物活性

纯度:还原SDS-PAGE测定大于95%

内毒素:经LAL测试,小于0.1 ng/ug (1 EU/ug)

存储及稳定性:存放温度≤-70℃,收货后可稳定存放6个月。开封后,在无菌条件下保存3个月,保存温度≤-70℃。请尽量减少冻融循环。


生物活性:CPE的活性形式是切割肽的c端氨基酸残基,因此参与肽激素和胰岛素、脑啡肽等神经递质的生物合成。膜相关的CPE作为一种分选受体,靶向调节的分泌蛋白,主要是垂体的跨高尔基网络和分泌颗粒中的激素前和神经肽进入分泌通路。该蛋白的缺陷与II型糖尿病有关,可导致葡萄糖清除受损和胰岛素抵抗。

化学性质
储存条件 粉末型式       -20°C   3年;4°C   2年
溶于溶剂       -80°C   6个月;-20°C   1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Kwan Yi Chu, et al. Islets. Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells

[2] Heping Zhang, et al. Mol Brain. Regulation of dopamine transporter activity by carboxypeptidase E

[3] Chun-Fa Zhang, et al. Biochem J. Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts

[4] O Varlamov, et al. J Biol Chem. The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing

[5] E Manser, et al. Biochem J. Processing and secretion of human carboxypeptidase E by C6 glioma cells

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.

Recombinant Human USP14 (E.coli, N-6His)

USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.





关键词:Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His), Carboxypeptidase H; Enkephalin convertase, Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His), Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His)溶解度, Recombinant Human Carboxypeptidase E/CPE (Mammalian,C-6His)结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号