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Recombinant Human IL31RA Protein (HEK293, C-hFc) 重组人IL31RA蛋白 (HEK293, C-hFc)

目录号 M40924 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


The recombinant human IL31RA consists 735 amino acids and predicts a molecular mass of 83.5 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with the Fc region of human IgG1 at the C-terminus.

Recombinant Human IL31RA Protein (HEK293, C-hFc)结构式

别名:interleukin 31 receptor A

规格 价格 库存状态
50ug ¥ 4725 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >90%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

The recombinant human IL31RA consists 735 amino acids and predicts a molecular mass of 83.5 kDa. A DNA sequence encoding the human IL31RA (Met1-Ser516) was expressed with the Fc region of human IgG1 at the C-terminus.

Immobilized human IL31-His at 10μg/mL (100μL/well) can bind human IL31RA-Fc, the EC50 of human IL31RA-Fc is 0.4-1.6 μg/mL.


Endotoxin < 1 EU/µg

Lyophilized from sterile PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 250 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Tal Kan et al. J Immunother Cancer. IL-31 induces antitumor immunity in breast carcinoma

[2] Shiri Davidi et al. Oncotarget. The antiangiogenic role of the pro-inflammatory cytokine interleukin-31

[3] Emilie Venereau et al. J Biol Chem. Definition and characterization of an inhibitor for interleukin-31

[4] Yuxin Zheng et al. 3 Biotech. Canine interleukin-31 binds directly to OSMRβ with higher binding affinity than to IL-31RA

[5] Chun-Kwok Wong et al. PLoS One. Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis

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