重组人TIMP-2蛋白(Mammalian,C-6His)是由哺乳动物表达系统产生的,目的基因编码Cys27-Pro220在c端表达6His标记。Accession #: P16035。
别名:Metalloproteinase Inhibitor 2; CSC-21K
表达系统:Mammalian
纯度:还原SDS-PAGE测定大于95%
内毒素:经LAL测试,小于0.1 ng/ug (1 EU/ug)
存储及稳定性:冻干蛋白应在< -20°C保存,但在室温下可保存3周。重组蛋白溶液可在4-7℃下保存2-7天。重组样品的等分液在< -20°C下稳定3个月
生物活性:金属蛋白酶组织抑制剂或TIMPs是调节锌酶的活化和蛋白水解活性的蛋白家族,被称为基质金属蛋白酶(MMPs)。组织金属蛋白酶抑制剂2 (TIMP-2)是一种非n -糖基化蛋白,分子量为22 kDa。它由多种细胞类型产生,通过形成二元复合物以非共价方式抑制基质金属蛋白酶,并通过结合其催化锌辅因子不可逆地失活基质金属蛋白酶。TIMP-2还具有促红细胞生长性和促细胞生长活性。
溶解性(25°C) | It is not recommended to reconstitute to a concentration less than 100 μg/ml. |
储存条件 |
粉末型式 -20°C 3年;4°C 2年 溶于溶剂 -80°C 6个月;-20°C 1个月 |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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