—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His) 重组人Arylsulfatase A/ARSA蛋白 (Mammalian, C-6His)

目录号 M21212 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, Recombinant Human Arylsulfatase A/ARSA expressed the target gene encoding Arg19-Ala507 with a 6His tag at the C-terminus.

Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His)结构式

别名:Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA

规格 价格 库存状态
10ug ¥ 1950 中国库存现货
50ug ¥ 5050 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down cerebroside 3-sulfate, a major component of myelin sheets, into cerebroside and sulfate. ARSA deficiency causes metachromatic leukodystrophy (MLD), a lysosomal storage disease of the central and peripheral nervous system with severe and progressive neurological symptoms. Recombinant human ARSA corresponds to the ARSA maturation peptide and has sulfatase activity.


Accession: AAH14210.2

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 50-65 KDa, reducing conditions

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, pH 8.0.

The product is shipped on dry ice. Upon receipt, store it immediately at the temperature listed below.

化学性质
性状 Solution
储存条件 Store at ≤ -70°C, stable for 6 months after receipt.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Jun Sung Lee, et al. Brain. Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone

[2] Sandra Pajarola, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Measurement of recombinant human arylsulfatase A and leukocyte sulfatase activities by analytical isotachophoresis

[3] Jonas Doerr, et al. Mol Ther. Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy

[4] Alessandra Biffi, et al. Science. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

[5] Kazumasa Fujita, et al. Connect Tissue Res. Mammalian arylsulfatase A functions as a novel component of the extracellular matrix

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.

Recombinant Human USP14 (E.coli, N-6His)

USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.





关键词:Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His), Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA, Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His), Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His)溶解度, Recombinant Human Arylsulfatase A/ARSA (Mammalian, C-6His)结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号