High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. Recombinant Human High Mobility Group Protein B1 is produced by Mammalian expression system, and the target gene encoding Gly2-Glu215 is expressed with a 6His tag at the C-terminus.
别名：High Mobility Group Protein B1
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
Recombinant Human High Mobility Group Protein B1 is produced by Mammalian expression system, and the target gene encoding Gly2-Glu215 is expressed with a 6His tag at the C-terminus.
Accession: P09429
APMol Mass: 25-30 KDa, reducing conditions
Endotoxin <1 EU/µg
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
This product is shipped on dry ice, store it immediately at the temperature listed below upon receipt.
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
[4] Ben Lu, et al. Nature. Novel role of PKR in inflammasome activation and HMGB1 release
[5] A Tesniere, et al. Oncogene. Immunogenic death of colon cancer cells treated with oxaliplatin
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