人中性粒细胞明胶酶相关脂质运载蛋白(Lipocalin-2/NGAL/LCN2)由大肠杆菌表达系统生产，编码Gln21-Gly198的目标基因在C端有一个6His标签。Protein number：P80188。
别名：Neutrophil gelatinase-associated lipocalin; NGAL
中性粒细胞明胶酶相关脂联素（LCN2）是一种分泌性蛋白，属于卡利辛超家族。这种蛋白在各种破坏性刺激后从受伤的肾小管细胞中释放出来，已经被肾脏病学家称为传入急性肾损伤（AKI）的最有希望的生物标志物之一。最近的证据还表明它在其他各种肾脏和非肾脏疾病中作为生物标志物的作用。此外，最近的研究似乎表明这一因素也可能参与慢性肾脏疾病的发生和发展。NGAL是第一个已知的哺乳动物蛋白，它能特异性地结合被称为苷酸盐的有机分子，这些分子是高亲和力的铁螯合剂。NGAL最早被称为天然免疫的抗菌因子和急性期蛋白，目前是参与肿瘤发展过程的最有趣和最神秘的蛋白质之一。作为细胞内铁载体和保护MMP9不被蛋白分解，NGAL具有明显的促肿瘤作用，在人类的不同肿瘤（如乳腺、胃、食道、脑）中已经被观察到。在甲状腺癌中，NGAL被NF-kB强烈诱导，NF-kB是参与肿瘤生长和慢性炎症与肿瘤发展之间联系的一个重要因素。因此，Lipocalin-2（LCN2/NGAL）已被牵涉到各种过程，包括细胞分化、增殖、生存和形态发生。
表观分子量：20-23 KDa, reducing conditions
内毒素 < 1 EU/µg
剂型描述：Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4。
蛋白浓度：0.6mg/ml
本产品由干冰包装运输，收到产品后，请立即将其保存在指定温度下。
| 性状 | Solution |
| 溶解性（25°C） | You can dilute the product with Sterile PBS solution |
| 储存条件 | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究