重组人IL-36RA蛋白(rhIL-36RA)原名 rhIL-1F5,可通过与 IL-1Rrp2 受体结合,拮抗 IL-36α,β或γ诱导的 NF-RrpB 信号传导,从而阻止功能信号的启动。
别名:Interleukin-36RA; IL-1F5
重组人IL-36RA蛋白(rhIL-36RA)原名 rhIL-1F5,可通过与 IL-1Rrp2 受体结合,拮抗 IL-36α,β或γ诱导的 NF-RrpB 信号传导,从而阻止功能信号的启动。IL-1 家族由 11 个结构相关的配体组成,包括新近重新命名的 IL-36RA(IL-1F5)、IL-36α(IL-1F6)、IL-36β(IL-1F8)和 IL-36γ(IL-1F9)。IL-36 配体与 IL-1Rrp2 受体(IL-1R6)的相互作用可诱导树突状细胞的成熟和活化。
重组人IL-36RA蛋白包含160个氨基酸,预测分子量为17.7kd。DNA序列编码人IL-36RA(NP_036407.1)表达带有His标签在C末端。
Endotoxin ≤0.01EU/ug
性状 | Lyophilized powder |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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