Cytokines and Growth Factors 细胞因子/生长因子 Cytokines and Growth Factors

目录号 产品名称 产品简介
M9370 Recombinant Human TNF α (HEK293, C-His) 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。
M9241 Recombinant Human EPO Protein (CHO) 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。
M9987 Recombinant Human PDGF-AA Protein (HEK293) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M9981 Recombinant Human IL-11 Protein (E. coli) 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。
M21094 Recombinant Rat IL-1β (E. coli) 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
M10022 Recombinant Mouse GM-CSF Protein (CHO) 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。
M21343 Recombinant Mouse TIM-1/KIM-1/HAVCR (HEK293, C-6His) 重组小鼠甲肝病毒细胞受体1同源物是由哺乳动物表达系统生产的,编码Tyr22Thr212的目标基因在C端有一个6His标签。蛋白编号:Q5QNS5。
M21338 Recombinant Human FGF1/ECGF Protein (154AA, E.coli) FGF acid, also known as ECGF, FGF-1 and HBGF-1, is a non-glycosylated heparin-binding growth factor expressed in brain, kidney, retina, smooth muscle cells, bone stroma, osteoblasts, astrocytes and endothelial cells.
M21331 Recombinant Human CDH1 (HEK293, C-6His) Recombinant human Cadherin-1/E-Cadherin/CDH1 is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. Accession: P12830.
M21326 Recombinant Schistosoma Japonicum GST (E. coli) Glutathione S-Transferase (GST), an antioxidant enzyme, is involved in the primary cellular defense mechanism against reactive oxygen species. Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification.
M21278 Recombinant Mouse IL-12 (HEK293) Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine consisting of p35 and p40 subunits. IL‑12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells.
M21212 Recombinant Human Arylsulfatase A/ARSA (HEK293, C-6His) Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, Recombinant Human Arylsulfatase A/ARSA expressed the target gene encoding Arg19-Ala507 with a 6His tag at the C-terminus.
M21210 Recombinant Mouse IL-3 (E. coli) 白细胞介素-3 (IL-3)是一种多效细胞因子,属于白细胞介素家族。IL-3也被称为多集落刺激因子,因为它通过激活细胞内的Ras-Raf-ERK和JAK/STAT等途径刺激多系造血细胞的发育和集落形成。IL-3通过靶向抗凋亡的bcl-2基因家族抑制细胞凋亡并促进细胞生存。
M21205 Recombinant Human/Mouse/Rat Irisin (HEK293, N-6His) Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M21204 Recombinant Human/Mouse/Rat Irisin (HEK293, C-Fc) Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M21203 Recombinant Human/Mouse/Rat Irisin (HEK293, C-6His) Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.
M21202 Recombinant Human Lipocalin-2/NGAL/LCN2 (E. coli, C-6His) 人中性粒细胞明胶酶相关脂质运载蛋白(Lipocalin-2/NGAL/LCN2)由大肠杆菌表达系统生产,编码Gln21-Gly198的目标基因在C端有一个6His标签。Protein number:P80188。
M21201 Recombinant Mouse Lipocalin-2/NGAL Protein (HEK293, C-6His) Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury.
M21166 Recombinant Human IL32 (E.coli) 它能诱导各种细胞因子,如TNFA/TNF-α和IL8。它激活典型的细胞因子信号途径NF-kappa-B和p38 MAPK。Accession # P24001。
M21121 Recombinant Rat IL-10 (CHO) Interleukin-10 (IL-10) 属于IL-10家族,由许多免疫细胞产生,如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同源二聚体的形式分泌,与受体结合后可抑制多种细胞因子的合成,包括活化巨噬细胞和 Th2 细胞产生的 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。
M21072 Recombinant Mouse GDNF (CHO) 胶质神经营养因子,又称GDNF和ATF-1,是一种属于TGF-β家族的神经营养因子。GDNF 促进多巴胺能神经元的生存和分化,并增加其高亲和力的多巴胺摄取。
M21057 Recombinant Human TNF-β (E. coli) ED50 < 4.0 pg/ml,在有代谢抑制剂放线菌素D的情况下,用L-929小鼠纤维肉瘤细胞进行细胞毒性测定,对应的特异性活性>2.5 × 108 units/mg。
M20003 Recombinant Human IFN alpha2a (E.coli) 重组人干扰素Alpha-2a由大肠杆菌表达系统生产。蛋白编号:P01563。ED50 < 0.1 ng/ml,通过使用TF-1细胞的细胞毒性试验测量,对应的特异性活性> 1.0 × 107 units/mg。
M19995 Recombinant Human/Mouse/Rat TGF-β3 (HEK293) Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is involved incell differentiation, embryogenesis and development. It regulates molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development.
M19993 Recombinant Human B4GALT1 (HEK293, C-6His) Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291.
M19986 Recombinant Human CXCL6 (HEK293, C-6His) Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162.








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