重组人/小鼠/大鼠含纤连蛋白III型域蛋白5是由哺乳动物表达系统生产的，编码Asp32-Glu143的目标基因在C端有一个Fc标签。蛋白编号： Q8NAU1。
别名：Fibronectin type III domain-containing protein 5
种属：人/小鼠/大鼠
表达系统：Mammalian
纯度：通过还原SDS-PAGE测定，大于95%
内毒素：经LAL测试，小于0.1 ng/µg（1 EU/µg）
分子量：39.7 KDa
存储及稳定性：冻干的蛋白质应储存在<-20°C，尽管在室温下可稳定3周。重组的蛋白质溶液可在4-7°C储存2-7天。重组的样品等分在<-20°C下可稳定3个月。
生物活性：含纤连蛋白III型结构域的蛋白5，是鸢尾花素的前体，是由FNDC5基因编码的蛋白。人类鸢尾花素合成为一个212个氨基酸（aa）的前体，编码一个1型跨膜蛋白，有121个细胞外结构域（ECD），21个跨膜结构域和39个细胞质结构域。Irisin的ECD包含一个纤连蛋白III型结构域和多个糖基化位点。Irisin诱导过氧化物酶增殖体激活受体γ辅助因子1α（PGC1α）和解偶联蛋白1（UCP1）的表达，这是一种线粒体相关的代谢蛋白。Irisin诱导白色脂肪组织转变为代谢更活跃的米色脂肪组织。Irisin还调节大脑中神经细胞的分化和神经元的生长，并参与骨细胞的分化。
| 溶解性（25°C） | It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 |
粉末型式 -20°C 3年；4°C 2年 溶于溶剂 -80°C 6个月；-20°C 1个月 |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究