M9370
|
Recombinant Human TNF α (HEK293, C-His) |
重组人肿瘤坏死因子α（Recombinant Human TNF α）是一个同源三聚体，它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。 |
| M9413
|
Recombinant Human VEGF165 Protein (HEK293, C-His) |
Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子，它促进内皮细胞的增殖和存活，促进血管生成和血管通透性。 |
| M10922
|
Recombinant Mouse TGF-beta 1 Protein (Human Cells) |
重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子，其控制许多生物过程，包括免疫，分化，肿瘤抑制，肿瘤转移，衰老，迁移，伤口愈合，细胞凋亡，细胞分裂，脂肪生成和成骨。ED50为5-25 pg/ml |
| M9391
|
Recombinant Human TGF-β1 (CHO) |
重组人TGF-β1（Recombinant Human TGF-β1）是一种多功能细胞因子，调节细胞增殖、生长、分化和运动，以及细胞外基质的合成和沉积。 |
| M9241
|
Recombinant Human EPO Protein (CHO) |
促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子，主要以其在促红细胞生成中的作用而闻名，它负责刺激红系祖细胞的增殖和分化。 |
| M9402
|
Recombinant Human PDGF-BB Protein (HEK293, C-His) |
PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体，分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原，包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。 |
| M9987
|
Recombinant Human PDGF-AA Protein (HEK293) |
重组人PDGF-AA蛋白（Recombinant Human PDGF-AA Protein）是一种有效的促细胞分裂剂，适用于多种细胞类型，包括平滑肌细胞，结缔组织细胞，骨骼和软骨细胞以及一些血细胞。 |
| M9981
|
Recombinant Human IL-11 Protein (E. coli) |
重组人IL-11蛋白（Recombinant Human IL-11 Protein）是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。 |
| M21094
|
Recombinant Rat IL-1β (E. coli) |
白细胞介素-1β（IL-1β）是一种非分泌的促炎症细胞因子，主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定，ED50为 < 10.0 pg/ml，相当于比活性 > 1.0 × 108 units/mg。 |
| M10022
|
Recombinant Mouse GM-CSF Protein (CHO) |
重组小鼠GM-CSF蛋白是一种生长因子，可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生，包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml，对应于>2.0 × 107units/mg的比活性。 |
M19981
|
Recombinant Rat MIP-3 α/CCL20 (HEK 293) |
巨噬细胞炎性蛋白-3 (MIP-3α)，又称趋化因子(C-C motif)配体20 (CCL20)或肝激活调节趋化因子(LARC)，是CC趋化因子家族中的一种小细胞因子。Accession # P97884-1。 |
| M19980
|
Recombinant Mouse MIP-3α/CCL20 (E. coli) |
巨噬细胞炎性蛋白-3（MIP-3α），也称为趋化因子（C-C基序）配体20（CCL20）或肝激活调节的趋化因子，是属于CC趋化因子家族的一种小细胞因子。通过使用人类CCR6转染的小鼠BaF3细胞进行趋化性生物测定，生物活性在0.1-10.0 ng/ml 的浓度范围内。 |
| M19977
|
Recombinant Human PRCP (HEK293, C-6His) |
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. Accession: P42785. |
| M15109
|
Recombinant Mouse IL-10 (CHO) |
重组小鼠IL-10蛋白 (CHO) 属于 IL-10 家族，与 Epstein-Barr 病毒蛋白 BCRFI 具有 80% 以上的序列同源性。它由许多免疫细胞产生，例如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同型二聚体的形式分泌，并在与其受体结合后，抑制活化的巨噬细胞和 Th2 细胞合成多种细胞因子，包括 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。 |
| M15098
|
Recombinant Human PCSK9 (HEK293,C-6His) |
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. Accession #: Q8NBP7. |
| M15095
|
Recombinant Mouse RANKL (HEK293, N-6His) |
Recombinant Mouse RANKL/TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation. |
| M15093
|
Recombinant Human EpCAM/Trop1 (Expi293, C-His) |
上皮细胞粘附分子(EpCAM)，也被称为KS1/4、gp40、GA733-2、17-1A和TROP -1，是一个40 kDa的跨膜糖蛋白，由242个氨基酸(aa)的胞外结构域(有两个EGF样重复)、一个23 aa的跨膜片段和一个26 aa的细胞质结构域组成。 |
| M15087
|
Recombinant Human Wnt3a (E. coli) |
重组人WnT-3A蛋白由大肠杆菌表达系统产生。将编码人类WNT3A (Ser19-Lys352)的DNA序列与His标签融合。Accession #P56704。 |
| M15086
|
Recombinant Human TGF-beta 1 (HEK293) |
重组人转化生长因子β 1(TGFβ-1)是一种分泌蛋白，属于TGF-β家族。TGFβ-1具有多种细胞功能，包括控制细胞生长、细胞增殖、细胞分化和细胞凋亡。以抑制IL-4依赖性的TF-1人类红血病细胞增殖的能力来测量，其ED50值为4-40 pg/ml。 |
| M15085
|
Recombinant Mouse SHH (C25II, E.coli) |
Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. |
| M15084
|
Recombinant Mouse Sonic Hedgehog/Shh (E.coli) |
利用大肠杆菌表达系统制备了重组小鼠Sonic Hedgehog基因，并表达了编码Cys25-Gly198的目的基因。Accession #: Q62226。 |
| M15083
|
Recombinant Human Sonic Hedgehog/Shh (E.coli, C24II) |
重组人 Sonic Hedgehog 由大肠杆菌表达系统生产，并表达编码 Cys24-Gly197（C24II）的靶基因。 |
| M15081
|
Recombinant Human Prolactin/PRL (E.coli) |
利用大肠杆菌表达系统制备了重组人催乳素，并表达了编码Leu29-Cys227的目的基因。Accession #: P01236。 |
| M15080
|
Recombinant Human OSM (E.coli, N-6His) |
重组人Oncostatin M由大肠杆菌表达系统产生，编码Ala26-Arg221的目的基因在n端以6His标记表达。通过对TF-1细胞的剂量依赖性刺激来测定的ED50是0.2-1 ng/ml。 |
| M15079
|
Recombinant Human NT-3 (E.coli) |
利用大肠杆菌表达系统制备了重组人神经营养因子-3，并表达了编码Tyr139-Thr257的目的基因。Accession #: P20783。 |
| M15078
|
Recombinant Mouse Noggin/NOG (HEK293,C-6His) |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466.
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| M15077
|
Recombinant Mouse LIF (E.coli) |
Mouse Leukemia inhibitory factor（lif）is a secreted protein which belongs to the LIF/OSM family. LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
| M15076
|
Recombinant Mouse HGF (HEK293,C-6His) |
Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. |
| M15073
|
Recombinant Human HGF (HEK293, C-6His) |
HGF is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis.
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| M15072
|
Recombinant Human FGF-19 (E.coli, N-6His) |
重组人成纤维细胞生长因子19由大肠杆菌表达系统产生，编码Phe27-Lys216的目的基因在n端以6His标记表达。Accession #: O95750。 |
