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Recombinant Human TGF-beta 1 (Mammalian) 重组人TGF-beta 1蛋白 (Mammalian)

目录号 M15086 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人转化生长因子β 1(TGFβ-1)是一种分泌蛋白,属于TGF-β家族。TGFβ-1具有多种细胞功能,包括控制细胞生长、细胞增殖、细胞分化和细胞凋亡。以抑制IL-4依赖性的TF-1人类红血病细胞增殖的能力来测量,其ED50值为4-40 pg/ml。

Recombinant Human TGF-beta 1 (Mammalian)结构式

别名:Transforming Growth Factor Beta-1; TGF-Beta-1

规格 价格 库存状态
10ug ¥ 2250 中国库存现货
50ug ¥ 7000 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95% , Endotoxin < 0.01 EU/ug
  • COA
  • MSDS
生物活性

Recombinant Human TGF-beta 1 (TGFβ-1) performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members.

Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells, the ED50 is 4-40 pg/ml.

Recombinant Human Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.


Accession: P01137

APMol Mass: 13 KDa, reducing conditions

Endotoxin: < 0.01 EU/µg as determined by LAL test

Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.

化学性质
溶解性(25°C) Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Jun Li, et al. Kaohsiung J Med Sci. Circ_0001666 upregulation promotes intestinal epithelial cell fibrosis in pediatric Crohn's disease via the SRSF1/BMP7 axis

[2] Musubu Takahashi, et al. Int J Mol Sci. Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-β 1: Induction of Cystathionine γ-Lyase and Cystathionine β-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways

[3] Sean K Wang, et al. J Clin Invest. Microglia modulation by TGF-β1 protects cones in mouse models of retinal degeneration

[4] June-Hyung Kim, et al. Cell Death Dis. TTC3 contributes to TGF-β 1-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation

[5] Mohammad M Al-Qattan, et al. J Coll Physicians Surg Pak. Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6

[6] Senem Aykul, et al. Anal Biochem. Determination of half-maximal inhibitory concentration using biosensor-based protein interaction analysis

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关键词:Recombinant Human TGF-beta 1 (Mammalian), Transforming Growth Factor Beta-1; TGF-Beta-1, Recombinant Human TGF-beta 1 (Mammalian)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human TGF-beta 1 (Mammalian), Recombinant Human TGF-beta 1 (Mammalian)溶解度, Recombinant Human TGF-beta 1 (Mammalian)结构式








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