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Recombinant Mouse IL-10 (CHO) 重组小鼠IL-10蛋白 (CHO)

目录号 M15109 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组小鼠IL-10蛋白 (CHO) 属于 IL-10 家族,与 Epstein-Barr 病毒蛋白 BCRFI 具有 80% 以上的序列同源性。它由许多免疫细胞产生,例如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同型二聚体的形式分泌,并在与其受体结合后,抑制活化的巨噬细胞和 Th2 细胞合成多种细胞因子,包括 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。

Recombinant Mouse IL-10 (CHO)结构式

别名:Mouse Interleukin-10 Protein

规格 价格 库存状态
10ug ¥ 2000 中国库存现货
50ug ¥ 6000 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

重组小鼠IL-10蛋白 (CHO) 属于 IL-10 家族,与 Epstein-Barr 病毒蛋白 BCRFI 具有 80% 以上的序列同源性。它由许多免疫细胞产生,例如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同型二聚体的形式分泌,并在与其受体结合后,抑制活化的巨噬细胞和 Th2 细胞合成多种细胞因子,包括 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。重组白细胞介素-10 (IL-10)还显示出抑制抗原呈递细胞 (APC) 功能的能力。

使用MC/9细胞的增殖试验中测量的ED50为 < 0.2 ng/ml。


Accession #: P18893

Apparent Molecular Weight: 21~23 kDa, on SDS-PAGE under reducing conditions.

Lyophilized after extensive dialysis against PBS.

化学性质
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml
储存条件 Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Mira Jung, et al. Basic Res Cardiol. IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation

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