重组小鼠IL-10蛋白 (CHO) 属于 IL-10 家族,与 Epstein-Barr 病毒蛋白 BCRFI 具有 80% 以上的序列同源性。它由许多免疫细胞产生,例如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同型二聚体的形式分泌,并在与其受体结合后,抑制活化的巨噬细胞和 Th2 细胞合成多种细胞因子,包括 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。
别名:Mouse Interleukin-10 Protein
重组小鼠IL-10蛋白 (CHO) 属于 IL-10 家族,与 Epstein-Barr 病毒蛋白 BCRFI 具有 80% 以上的序列同源性。它由许多免疫细胞产生,例如 T 细胞、巨噬细胞、肥大细胞和树突状细胞。它通常以同型二聚体的形式分泌,并在与其受体结合后,抑制活化的巨噬细胞和 Th2 细胞合成多种细胞因子,包括 IFN-γ、IL-2、IL-3、TNF 和 GM-CSF。重组白细胞介素-10 (IL-10)还显示出抑制抗原呈递细胞 (APC) 功能的能力。
使用MC/9细胞的增殖试验中测量的ED50为 < 0.2 ng/ml。
Accession #: P18893
Apparent Molecular Weight: 21~23 kDa, on SDS-PAGE under reducing conditions.
Lyophilized after extensive dialysis against PBS.
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml |
储存条件 | Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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