Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is involved incell differentiation, embryogenesis and development. It regulates molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development.
别名:Transforming growth factor beta-3; TGFB3
转化生长因子3(TGF -β 3, TGFB3)是TGF -β超家族的成员,其结构和功能相似。TGFB3作为LAP的复合体分泌。这种潜在的tgfb3在纤溶蛋白、基质金属蛋白酶、凝血反应蛋白-1和一部分整合蛋白裂解时变得活跃。它与II型丝氨酸/苏氨酸激酶受体TGF- β RII高亲和力结合。TGFB3参与细胞分化、胚胎发生和发育。它被认为是调节味蕾发育过程中参与细胞粘附和细胞外基质(ECM)形成的分子。如果没有TGF-β3,哺乳动物就会出现被称为腭裂的畸形。
Recombinant Human/Mouse/Rat Transforming Growth Factor Beta 3 expressed the target gene encoding Ala301-Ser412(Tyr340Phe).
Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells, the ED50 for this effect is 10-80 pg/ml.
Accession: P10600
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: 12-14 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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