重组人Cadherin-1/E-Cadherin/CDH1由哺乳动物表达系统生产，编码Asp155-Ile707的目标基因在C端带有6His标签。蛋白编号：P12830。
别名：Cadherin-1; CDH1;CAM 120/80;E-cadherin; CD324
种属：Human
表达系统：Mammalian
纯度：通过还原SDS-PAGE测定，大于95%
内毒素：经LAL测试，小于0.1 ng/µg（1 EU/µg）
分子量：61.2 KDa
存储及稳定性：冻干的蛋白质应储存在<-20°C，尽管在室温下可稳定3周。重组的蛋白质溶液可在4-7°C储存2-7天。重组的样品等分在<-20°C下可稳定3个月
生物活性：E-卡德林是卡德林超家族的一个经典成员。编码的蛋白是一种钙依赖性的细胞-细胞粘附糖蛋白，由五个细胞外卡德林重复序列、一个跨膜区和一个高度保守的细胞质尾部组成。该基因的突变与胃癌、乳腺癌、结直肠癌、甲状腺癌和卵巢癌有关。功能的丧失被认为是通过增加增殖、侵袭和/或转移而促进了癌症的进展。该蛋白的外域介导细菌对哺乳动物细胞的粘附，而细胞质域是内化所需的。已确定的转录变体来自共识剪接位点的突变。另外，E-Cadherin具有强大的抑制入侵的作用，它是整合素α-E/β-7的配体。
| 溶解性（25°C） | It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 |
粉末型式 -20°C 3年；4°C 2年 溶于溶剂 -80°C 6个月；-20°C 1个月 |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究