M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7995
|
Pranlukast hemihydrate |
Pranlukast is a subtype specific CysLT1 receptor antagonist. |
| M7993
|
PalGly |
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. |
| M7990
|
Pyocyanin |
Pyocyanin, a blue-green pigment belonging to phenazine pigments, is a redox-active phenazine. |
| M7986
|
OM137 |
OM137 is an inhibitor of aurora kinases; inhibitor of spindle checkpoint. |
| M7985
|
Olprinone hydrochloride |
Selective phosphodiesterase 3 (PDE3) inhibitor. |
| M7984
|
Opipramol dihydrochloride |
σ1/σ2 opioid receptor agonist; an antagonist at D2, 5HT2 and H1 receptors; atypical antidepressant, antipsychotic and anxiolytic. |
| M7983
|
9,12-Octadecadiynoic acid |
Potent cyclooxygenase and lipoxygenase inhibitor. |
| M7981
|
Oxamflatin |
Histone deacetylase inhibitor; anti-cancer agent. |
| M7978
|
OPC 31260 hydrochloride |
OPC 31260 hydrochloride是OPC 31260的盐酸盐形式，同时也是一种血管加压素V2受体（Vasopressin V2 receptor (V2R)）的选择性拮抗剂。 |
| M7977
|
Octoclothepin maleate salt |
Octoclothepin maleate salt is a D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist. |
| M7976
|
Oxotremorine M |
Nonselective muscarinic acetylcholine receptor agonist. |
| M7974
|
Netropsin dihydrochloride |
Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. |
| M7973
|
NSC 295642 |
NSC 295642 is a potent inhibitor of cell migration. |
| M7972
|
NSC308848 |
NSC308848 is a small molecular transcription factor inhibitor. |
| M7971
|
NSC727447 |
NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. |
| M7970
|
NIDA-41020 |
NIDA-41020 is a CB1 cannabinoid receptor antagonist. |
| M7969
|
NS3694 |
NS3694 is an Inhibitor of apoptosome formation. |
| M7968
|
7-Nitroindazole |
Selective inhibitor of nitric oxide synthase from mouse brain. |
| M7967
|
NN-DNJ |
NN-DNJ is a glucosidase inhibitor that acts as a pharmacologic chaperone. |
| M7965
|
Neridronate |
Neridronate is a bone resorption inhibitor. |
