M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7888
|
Levocabastine hydrochloride |
Non-peptide histamine H1 receptor antagonist; neurotensin NTS2 receptor ligand. |
| M7884
|
Lidocaine N-ethyl chloride |
Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker. |
| M7883
|
L-741,626 |
Selective D2 dopamine receptor antagonist. |
| M7882
|
Levallorphan tartrate salt |
Partial agonist (antagonist) at μ and δ opioid receptors. |
| M7881
|
LY-487379 hydrochloride |
LY-487379 is a positive allosteric modulator of the metabotropic glutamate receptor mGluR2. |
| M7875
|
KRM-III |
KRM-III is an inhibitor of T cell antigen receptor (TCR), an inhibitor of phorbol myristate acetate (PMA) /ionomycin-induced nuclear factor of activated T cells (NFAT) activation and T cell proliferation. |
| M7868
|
JFD00244 |
JFD00244 is a SIRT (sirtuin, human silent information regulator) inhibitor. |
| M7864
|
JS-K |
Nitric oxide donor; antiproliferative. |
| M7862
|
IMS2186 |
IMS2186 is an anti-proliferative and anti-angiogenic agent. |
| M7861
|
H-7 |
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C. |
| M7860
|
ISCK03 |
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. |
| M7859
|
Idazoxan hydrochloride |
α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. |
| M7858
|
Ibandronate sodium salt |
Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). |
| M7856
|
Immepip dihydrobromide |
Immepip is a H3 and H4 histamine receptor agonist. |
| M7855
|
ICI 192605 |
ICI 192605 is a potent thromboxane A2 receptor antagonist. |
| M7854
|
Ilmofosine |
Protein Kinase C (PKC) inhibitor; an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. |
| M7852
|
I-AB-MECA |
Reference standard for radioiodinated I-AB-MECA, a widely used, high affinity radioligand for the A3 adenosine receptor. |
| M7851
|
ITX3 |
ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. |
| M7850
|
1,5-Isoquinolinediol |
DiQ is a potent inhibitor of Poly(ADP-ribose) synthetase which is activated by nitric oxide; neuroprotective agent. |
| M7849
|
Imetit dihydrobromide |
Potent and selective H3 histamine receptor agonist. |
