M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7808
|
FR-900098 monosodium salt |
1-脱氧-d -木酮糖5-磷酸还原异构酶(DXR)是一种酶，在革兰氏阴性、革兰氏阳性细菌、植物和导致最致命疟疾的疟原虫——恶性疟原虫(哺乳动物产生)的非甲戊酸途径中，参与类异戊二烯生物合成的第一步。 |
| M7807
|
Fusaric acid |
Dopamine β-hydroxylase inhibitor. |
| M7806
|
Fluorocurarine chloride |
Short-acting selective sympathetic ganglioblocker with weak antagonist activity on the nicotinic receptor at the neuromuscular junction; hypotensive. |
| M7805
|
Fasentin |
Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor. |
| M7803
|
FAUC 213 |
Highly selective D4 dopamine receptor full antagonist. |
| M7801
|
6-Fluoromevalonate |
Mevalonate-pyrophosphate decarboxylase inhibitor. |
| M7800
|
Fenvalerate |
Type II pyrethroid. |
| M7799
|
Norfluoxetine hydrochloride |
Fluoxetine metabolite; more potent inhibitor of serotonin uptake than fluoxetine with a half-life in vivo of 5-7 days. |
| M7798
|
FPL 64176 |
Potent Ca2+ channel (L-type) activator. |
| M7797
|
FPL-55712 |
CysLT1 leukotriene receptor antagonist. |
| M7794
|
Encainide hydrochloride |
Encainide hydrochloride is a sodium channel blocker and class Ic antiarrhythmic. |
| M7789
|
Exo2 |
Exo2 acts as a chemical probe of intracellular transport. |
| M7788
|
Ethopropazine hydrochloride |
Ethoproprazine hydrochloride is an inhibitor of butyrylcholinesterase; antiparkinsonian. |
| M7787
|
Eupatorin |
Eupatorin acts as an antiproliferative in cells expressing the CYP1A- family. |
| M7786
|
17-Epiestriol |
17-雌二醇是一种雌二醇代谢物，也是一种选择性雌激素受体(ER) -激动剂。 |
| M7784
|
16-Epiestriol |
16-Epiestriol is an estradiol metabolite that exhibits significant anti-inflammatory activity without glycogenic activity. |
| M7783
|
Efaroxan hydrochloride |
(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I1 imidazoline binding site antagonist. |
| M7781
|
7-Ethoxycoumarin |
Substrate for CYP2B6. |
| M7780
|
116-9e |
116-9e是Hsp40-Hsp70结合的阻断剂，从而抑制Hsp70-Hsp40的伴侣活性。 |
| M7777
|
Donitriptan monohydrochloride |
Donitriptan is a potent, selective 5-HT1B/1D agonist. |
