M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M8039
|
CP-226269 |
CP-226269 is a D4 dopamine receptor agonist with EC50 of 32 nM. |
| M8036
|
PF-04479745 |
PF-04479745 (PF-4479745) is a selective serotonin 5HT2C agonist. |
| M8035
|
PF-03882845 |
PF-03882845 is a potent non-steroidal mineralocorticoid antagonist with and IC50 of 0. |
| M8031
|
Psychosine from bovine brain |
Glycolipid precursor of cerebrosides. |
| M8030
|
PB28 dihydrochloride |
Selective σ2 opioid receptor ligand; putative σ2 agonist. |
| M8025
|
Protopine hydrochloride |
Protopine hydrochloride is a Ca2+ channel blocker and antiplatelet agent. |
| M8024
|
Propionylpromazine hydrochloride |
Phenothiazine antipsychotic; D2 dopamine receptor antagonist. |
| M8021
|
SC 22716 |
Cell-permeable leukotriene A4 (LTA4) hydrolase inhibitor that suppresses LTB4 production. |
| M8017
|
PTACH |
HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard). |
| M8016
|
PD-118057 |
PD-118057 is an activator of ether-a-go-go-related (hERG) potassium channel. |
| M8012
|
Papaverine hydrochloride |
Smooth muscle relaxant and cerebral vasodilator; phosphodiesterase inhibitor. |
| M8011
|
Ponasterone A |
Ponasterone A is an insect hormone, involved in regulating metamorphosis. |
| M8010
|
Phloridzin dihydrate |
Competitive inhibitor of SGLT1 and SGLT2. |
| M8009
|
Pipamperone dihydrochloride |
D2 dopamine receptor antagonist; 5-HT2 serotonin receptor antagonist; antipsychotic. |
| M8006
|
PD 404,182 |
Potential antibiotic of gram negative bacteria. |
| M8005
|
PD 168,077 maleate salt |
Selective D4 dopamine receptor agonist. |
| M8003
|
(+)-PD 128,907 hydrochloride |
Selective D3 dopamine receptor agonist. |
| M8000
|
Pirenperone |
5-HT2血清素受体拮抗剂。 |
| M7999
|
8-PIP-cAMP |
Selective cAMP-dependent protein kinase (PKA) activator. |
| M7998
|
PET-cGMP |
cGMP-dependent protein kinase (PKG I and PKG II) activator. |
