M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M8162
|
SKF-83959 hydrobromide |
D1 dopamine receptor agonist. |
| M8161
|
SE 175 |
An organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide. |
| M8158
|
SDZ-205,557 hydrochloride |
Potent, selective 5-HT4 serotonin receptor antagonist. |
| M8157
|
Sordarin sodium salt |
Sordarin is an antifungal metabolite possessing a tetracyclic diterpene glycoside structure. |
| M8155
|
SID7969543 |
SID7969543 is a SF-1 (or NR5A1) inhibitor. |
| M8153
|
N-Methylspiperone hydrochloride |
D2 dopamine receptor antagonist. |
| M8152
|
ST638 |
Protein tyrosine kinase inhibitor (IC50 = 370 nM). |
| M8150
|
SB-668875 |
SB-668875 is a novel, selective peptide agonist at OX2 orexin receptors. |
| M8148
|
LY-165,163 |
Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. |
| M8147
|
RX 821002 hydrochloride |
Selective α2-adrenoceptor antagonist. |
| M8145
|
Ro4368554 |
Ro4368554 is a 5-HT6 receptor antagonist. |
| M8143
|
Razoxane |
Razoxane is clinically active against angiogenesis and metastasis. |
| M8142
|
RRD-251 hydrochloride |
RRD-251 hydrochloride is a reversible, potent, and selective disruptor of Rb/Raf-1 interaction. |
| M8140
|
REV 5901 |
Leukotriene D4 receptor antagonist. |
| M8139
|
Ridaifen-B |
Ridaifen-B (RID-B) is a novel tamoxifen (TAM) analog that significantly augments apoptosis-inducing effect of TAM in estrogen receptor (ER)-negatives cells. |
| M8138
|
RU 26752 |
RU 26752 is a mineralocorticoid receptor antagonist. |
| M8137
|
RK-682 |
RK-682 是一种特异性和非竞争性的蛋白酪氨酸磷酸酶抑制剂，能抑制 CD45 和 VHR 的去磷酸化活性，对 PTP1B 的 IC50 分别为 54 μM、2.0 μM和 4.5 μM。 |
| M8135
|
Rhodblock 1a |
Rhodblock 1a is an inhibitor of the Rho Kinase pathway. |
| M8134
|
RU7 |
RU7 is a selective inhibitor of bacterial β-clamp interaction with DNA polymerase POL III, and an inhibitor of a DNA polymerase sliding clamp. |
| M8133
|
Ro 31-0432 |
Protein kinase C (PKC) inhibitor; membrane-derived PKC inhibitor. |
