找到约 48 条 “Transferase” 相关结果 （用时 0.13 秒）
| 目录号 | 产品名称 | 中文名称 | 靶点 |
|---|---|---|---|
M3008
|
SGI-1027 | SGI-1027 | DNA Methyltransferase |
| DNA Methyltransferase Inhibitor II | |||
| SGI-1027是一种DNMT抑制剂，作用于DNMT1， DNMT3A和DNMT3B，IC50分别为6， 8和7.5 μM。 | |||
| M4898
|
Histone Acetyltransferase Inhibitor II | Histone Acetyltransferase Inhibitor II | Histone Acetyltransferase |
| Histone Acetyltransferase Inhibitor II, 调节胰岛素分泌血糖,特别是胰岛素,应对生理信号。 | |||
| M19993
|
Recombinant Human B4GALT1 (HEK293, C-6His) | 重组人B4GALT1 蛋白(HEK293, C-6His) | Cytokines and Growth Factors |
| 1,4- galactosyltransferase, polypeptide 1; B4GalT1 | |||
| Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291. | |||
| M21326
|
Recombinant Schistosoma Japonicum GST (E. coli) | 谷胱甘肽 S 转移酶 | Cytokines and Growth Factors |
| Glutathione S-transferase class-mu 26 kDa isozyme; GST 26 | |||
| Glutathione S-Transferase (GST), an antioxidant enzyme, is involved in the primary cellular defense mechanism against reactive oxygen species. Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. | |||
| M31144
|
γ-Glutamyl Transferase (from hog kidney) | γ-谷氨酰转肽酶 (from hog kidney) | Enzymes & Coenzymes |
| γ-glutamyl transpeptidase; gamma-Glutamyl Transferase; GGT; γ-GT | |||
| γ-谷氨酰转肽酶又称γ-谷氨酰转移酶、GGT、γ-GT，是一种转移酶，在γ-谷氨酸官能团从谷胱甘肽等分子上转移至受体时起催化作用，受体可能是一种氨基酸、一种肽或水。γ-谷氨酰转肽酶在γ-谷氨酰循环中起着关键作用。 | |||
| M31145
|
γ-Glutamyl Transferase (from bovine kidney) | γ-谷氨酰转肽酶 (from bovine kidney) | Enzymes & Coenzymes |
| γ-glutamyl transpeptidase; gamma-Glutamyl Transferase; GGT; γ-GT | |||
| γ-谷氨酰转肽酶又称γ-谷氨酰转移酶、GGT、γ-GT，是一种转移酶，在γ-谷氨酸官能团从谷胱甘肽等分子上转移至受体时起催化作用，受体可能是一种氨基酸、一种肽或水。γ-谷氨酰转肽酶在γ-谷氨酰循环中起着关键作用。 | |||
| M40919
|
Recombinant Human GSTM2 Protein (E. coli, His Tag) | 重组人GSTM2蛋白 (E. coli, His Tag) | Cytokines and Growth Factors |
| Glutathione S-transferase Mu 2; GST class-mu 2 | |||
| Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. A DNA sequence encoding the native human GSTM2 (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus. | |||
| M42354 | Alanine aminotransferase | Alanine aminotransferase | Metabolite/Endogenous Metabolite |
| Alanine aminotransferase 是一种吡哆醛酶，可催化 L-丙氨酸和 2-氧代谷氨酸可逆地相互转化为丙酮酸和 L-谷氨酸。 | |||
| M42891 | Gamma-Glutamyl Transferase-IN-1 | Gamma-Glutamyl Transferase-IN-1 | Others |
| Gamma-Glutamyl Transferase-IN-1 是一种具有抗真菌和抗菌活性的 β-羰基酰肼类抑制剂，靶向谷氨酰转移酶 (gamma-glutamyl transferase)。 | |||
| M42892 | Gamma-Glutamyl Transferase-IN-2 | Gamma-Glutamyl Transferase-IN-2 | Others |
| Gamma-Glutamyl Transferase-IN-2 是一种具有抗真菌和抗菌活性的 β-羰基酰肼类抑制剂，靶向谷氨酰转移酶 (gamma-glutamyl transferase)。 | |||
| M43259 | O-Linked GlcNAc transferase substrate | O-Linked GlcNAc transferase substrate | Others |
| O-Linked GlcNAc transferase substrate 是一种有生物活性的肽。 | |||
| M50283 | Glutathione S-transferase | Glutathione S-transferase | Enzymes & Coenzymes |
| Glutathione S-transferase 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M50331 | Carnitine acetyltransferase | Carnitine acetyltransferase | Enzymes & Coenzymes |
| Carnitine acetyltransferase 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M50341 | Chloramphenicol acetyltransferase | Chloramphenicol acetyltransferase | Enzymes & Coenzymes |
| Chloramphenicol acetyltransferase (CAT) 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M50345 | Galactose 1-phosphate uridylyltransferase | Galactose 1-phosphate uridylyltransferase | Enzymes & Coenzymes |
| Galactose-1-phosphate uridyl transferase 催化半乳糖代谢 Leloir 途径的第二步，即半乳糖转化为葡萄糖。 | |||
| M50346 | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase | Enzymes & Coenzymes |
| Pyrophosphate-fructose 6-phosphate 1-phosphotransferase (PFP1) 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M51728 | Galactosyltransferase | Galactosyltransferase | Others |
| Galactosyltransferase 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。 | |||
| M58556
|
Recombinant Human ACAA2 Protein (E. coli, N-His) | 重组人ACAA2 蛋白 (E. coli, N-His) | Cytokines and Growth Factors |
| Acetyl-CoA acyltransferase | |||
| Recombinant Human ACAA2 Protein (E. coli, N-His) expressed the target gene encoding Arg90-Ala397 with an N-His tag. | |||
| M58557
|
Recombinant Human ACAA1 Protein (E. coli, N-His) | 重组人ACAA1 蛋白 (E. coli, N-His) | Cytokines and Growth Factors |
| Peroxisomal 3-oxoacyl-CoA thiolase; Acetyl-CoA C-myristoyltransferase; Acetyl-CoA acyltransferase | |||
| Recombinant Human ACAA1 Protein (E. coli, N-His) expressed the target gene encoding Gly182-Asn424 with an N-His tag. | |||
| M11322
|
JBSNF-000088 | 6-甲氧基-3-吡啶羧胺 | Others |
| 6-Methoxynicotinamide | |||
| JBSNF-000088 (6-Methoxynicotinamide)是一种 烟酰胺（NA）的类似物，是 Nicotinamide N-methyltransferase (NNMT) 的有效抑制剂，对 human NNMT(hNNMT)、monkey NNMT (mkNNMT) 和 mouse NNMT (mNNMT)的IC50值为1.8 µM、2.8 µM 和 5.0 µM。 | |||
| M2024
|
BIX 01294 Trihydrochloride | BIX 01294 Trihydrochloride | Histone Methyltransferase |
| BIX 01294是一种组蛋白甲基转移酶（G9ahistone methyltransferase）抑制剂，IC50为2.7 μM，降低组蛋白H3K9me2，也微弱抑制GLP（主要是H3K9me3），对其他组蛋白甲基转移酶没有显著的抑制活性。此外，BIX-01294可用于小鼠多能干细胞的诱导和维持。 | |||
M2198
|
Curcumin | 姜黄素 | Histone Acetyltransferase |
| Indian Saffron; Turmeric yellow; Natural Yellow 3; Diferuloylmethane | |||
| Curcumin (Diferuloylmethane，姜黄素)是一种天然酚类化合物，同时也是特异性的乙酰转移酶 p300/CREB 结合蛋白抑制剂，能抑制组蛋白/非组蛋白的乙酰化，以及组蛋白乙酰转移酶（histone acetyltransferase）依赖的染色质转录。此外，Curcumin 对 NF-κb 和 MAPKs 有抑制作用，并能通过 Keap1 半胱氨酸修饰诱导 Nrf2 蛋白的稳定。具有抗炎、抗氧化、抗增殖和抗血管生成活性。Curcumin 也是一种铜离子载体，可促进细胞对铜离子的摄取，它可以上调肠腺癌细胞中铜死亡相关蛋白并诱导其发生铜死亡。 | |||
| M2482
|
C646 | C646 | Histone Acetyltransferase |
| C 646 | |||
| C646是一种选择性的 histone acetyltransferase（组蛋白乙酰转移酶）抑制剂，抑制p300，Ki为400 nM，比作用于其他乙酰转移酶选择性高。 | |||
| M2804
|
LB42708 | LB42708 | Farnesyl Transferase |
| LB42708 是一种具有口服活性的，有效的 farnesyltransferase (FTase) 抑制剂，还可通过阻断内皮细胞中MAPKK/ERK/MAPK和PI3K/Akt/eNOS途径，抑制VEGF诱导的Ras活化。 | |||
| M2819
|
Lomeguatrib | 罗米鲁曲 | DNA Methyltransferase |
| PaTrin-2 | |||
| Lomeguatrib是一种有效的O6-alkylguanine-DNA-alkyltransferase抑制剂，IC50为5 nM。 | |||
| M3135
|
Zebularine | 泽布拉林 | DNA Methyltransferase |
| NSC309132; 4-Deoxyuridine | |||
| Zebularine（泽布拉林）是一种DNA methylation（DNA甲基化）抑制剂，与DNA methyltransferases（DNA甲基化转移酶）形成共价复合物，也抑制胞苷脱氨酶，Ki为2 μM。 | |||
| M11199
|
Myriocin | 多球壳菌素 | Anti-infection |
| Thermozymocidin; ISP-I | |||
| Myriocin 是一种从 Myriococcum albomyces, Isaria sinclairi 和 Mycelia sterilia 中分离的真菌代谢产物，是一种有效的丝氨酸-棕榈酰转移酶 (serine-palmitoyl-transferase) 抑制剂，是鞘脂从头合成的关键。 | |||
| M5946
|
Salirasib | 沙利雷塞 | Ras |
| S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS | |||
| Salirasib是一种有效的竞争性prenylated protein methyltransferase (PPMTase)抑制剂， Ki为2.6 μM，其抑制Ras甲基化。Phase 2。 | |||
| M5128
|
PFI-2 | PFI-2 | Histone Methyltransferase |
| (R)-PFI-2 | |||
| PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. | |||
| M6177
|
SGC2085 | SGC2085 | PRMTs |
| SGC2085是一种有效的、选择性的Coactivator Associated Arginine Methyltransferase 1 (CARM1)抑制剂，IC50为50 nM，比对其他PRMTs的选择性高100倍以上。 | |||
| M7085
|
OR-486 | OR-486 | Others |
| OR-486 is a catechol O-methyltransferase inhibitor. | |||
| M7509
|
UNC0642 | UNC0642 | Histone Methyltransferase |
| UNC0642是一种有效的、选择性的histone methyltransferases G9a/GLP抑制剂，对G9a和GLP的IC50均小于2.5 nM。对G9a和GLP的选择性比其他激酶、GPCRs、转运体和离子通道高300倍以上。 | |||
| M7584
|
2-Bromohexadecanoic acid | 2-溴十六烷酸；2-溴棕榈酸 | Pyroptosis |
| 2-Bromopalmitic acid; 2-Bromopalmitate; 2-BP | |||
| 2-Bromohexadecanoic acid 是一种 2-溴棕榈酸，同时也可作为棕榈酰化 (palmitoylation) 抑制剂，抑制棕榈酰基转移酶 (palmitoyl acyl transferase，PAT) 对MyrGCK(NBD)和FarnCNRas(NBD)的活性，IC50均接近4 µM。2-Bromohexadecanoic acid 抑制所有 DHHC (Asp-His-His-Cys) 蛋白的棕榈酰转移酶活性。 | |||
| M7631 | B581 | B581 | Farnesyl Transferase |
| B-581 | |||
| B581 is a membrane permeable inhibitor of farnesyltransferase. | |||
| M7661 | BMS-214662 hydrochloride | BMS-214662 hydrochloride | Farnesyl Transferase |
| BMS-214662是一种口服有效的、有效的、选择性的法尼酰基转移酶 farnesyltransferase (FTase) 抑制剂，可减少NF90-8和ST88-14鞘瘤(MPNST)细胞系中的Ras prenylation。 | |||
| M7679 | Acetylethylcholine mustard hydrochloride | Acetylethylcholine mustard hydrochloride | Others |
| Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase. | |||
| M8196
|
Sinefungin | 西奈芬净 | Histone Methyltransferase |
| Adenosyl-Ornithine; A-9145 | |||
| Sinefungin（Adenosyl-Ornithine，西奈芬净）是一种与S-腺苷甲硫氨酸相关的天然核苷，可从链霉菌属物种中分离得到。此外，Sinefungin还可以抑制DNA甲基转移酶（DNA methyltransferase）的活性，阻断DNA和RNA中碱基的甲基化，从而抑制DNA合成。具有抗真菌、抗病毒和抗寄生虫活性。 | |||
| M8245 | SPV-106 | SPV-106 | Others |
| SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. | |||
| M8276
|
Pleuromutilin | 泰妙菌素 | Antibiotic |
| Drosophilin B; Mutilin 14-glycolate | |||
| Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation. | |||
| M8451 | SW155246 | SW155246 | Others |
| SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor that demethylates cytosines in vivo in a cell-based assay without affecting protein levels or generating reactive oxygen species. | |||
| M8467 | OF-1 | OF-1 | Others |
| OF-1 is a chemical probe for the bromodomains of the BRPF (BRomodomain and PHD Finger containing) family of scaffolding proteins (BRPF1, BRPF2, BRPF3) that assemble histone acetyltransferase (HAT) complexes of the MYST family members MOZ and MORF. | |||
| M8558
|
DC_05 | DC_05 | DNA Methyltransferase |
| DC_05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor that significantly inhibits cancer cell proliferation. | |||
| M8649
|
GSK591 | GSK591 | PRMTs |
| GSK-591; GSK3203591; EPZ015866 | |||
| GSK591 (EPZ015866) 是一种有效的，选择性的 protein methyltransferase 5 (PRMT5) 抑制剂，其 IC50 值为 4 nM。 | |||
| M8694
|
K-604 | K-604 | Others |
| K-604 inhibits against acyl-coenzyme A (acyl-CoA):cholesterol O-acyltransferase-1 (ACAT1, SOAT1) activitiy in a selective (IC50 = 450 nM vs. | |||
| M8989
|
BIX-01294 | BIX-01294 | Histone Methyltransferase |
| BIX-01294 是一种有效的G9a甲基转移酶 (G9a Histone Methyltransferase) 抑制剂，IC50 值为 1.9 μM。此外，BIX-01294可用于小鼠多能干细胞的诱导和维持。BIX-01294 可诱导坏死性凋亡 (necroptosis) 和自噬。 | |||
| M9445
|
YF2 | YF2 | Histone Acetyltransferase |
| YF-2 | |||
| YF2是一种选择性的组蛋白乙酰转移酶 (histone acetyltransferase) 激动剂，它对CBP，PCAF和GCN5的EC50值分别为2.75 μM，29.04 μM和49.31 μM。 | |||
| M9919
|
TH1834 | TH1834 | Histone Acetyltransferase |
| TH-1834 | |||
| TH1834 is a specific Tip60 (KAT5) histone acetyltransferase (HAT) inhibitor. | |||
| M13491
|
Amodiaquine dihydrochloride | Amodiaquine dihydrochloride | Parasite |
| Amodiaquin dihydrochloride | |||
| Amodiaquine dihydrochloride (Amodiaquin dihydrochloride) 是一种4-氨基喹啉类抗疟剂，是一种有效的具有口服活性的组胺 N-甲基转移酶 (histamine N-methyltransferase) 抑制剂，Ki 值为 18.6 nM。Amodiaquine dihydrochloride 也是一种 Nurr1 激动剂，可特异性结合 Nurr1 的配体结合域，EC50 为 ~20 μM。抗炎作用。 | |||
