M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7107
|
PD 90780 |
PD 90780 is a inhibits NGF binding to p75
NTR . |
| M7105
|
PD 158780 |
PD 158780 is a potent ErbB receptor family inhibitor. |
| M7101
|
Palmitoylisopropylamide |
Palmitoylisopropylamide is a inhibitor of FAAH. |
| M7099
|
PACMA 31 |
PACMA 31 is a irreversible protein disulfide isomerase (PDI) inhibitor. |
| M7098
|
PACAP 1-27 |
PACAP 1-27 is a potent stimulator of adenylyl cyclase. |
| M7096
|
P1075 |
P1075 is a potent K
ir6 (K
ATP) channel opener. |
| M7095
|
Ozagrel hydrochloride |
Ozagrel hydrochloride is a selective thromboxane A
2 synthetase inhibitor. |
| M7093
|
OXSI 2 |
OXSI 2 is a potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes. |
| M7092
|
Oxotremorine sesquifumarate |
Oxotremorine sesquifumarate is a muscarinic agonist. |
| M7091
|
Org 48762-0 |
Org 48762-0 is a selective p38α/β inhibitor; orally bioavailable. |
| M7090
|
Org 37684 |
Org 37684 is a 5-HT
2 agonist. |
| M7089
|
Org 25543 hydrochloride |
Org 25543 hydrochloride is a potent and selective GlyT2 inhibitor. |
| M7088
|
Org 24598 lithium salt |
Org 24598 lithium salt is a selective GlyT1 inhibitor. |
| M7087
|
Org 20599 |
Org 20599 is a positive allosteric modulator and direct agonist of GABA
A receptors. |
| M7086
|
Org 12962 hydrochloride |
Org 12962 hydrochloride is a selective 5-HT
2C agonist. |
| M7083
|
ONO 6818 |
ONO 6818 is a high affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active. |
| M7082
|
OMDM-2 |
OMDM-2 is a potent inhibitor of anandamide uptake. |
| M7081
|
Olomoucine |
Olomoucine is a cyclin-dependent kinase inhibitor. |
| M7077
|
Ocinaplon |
Ocinaplon is a gABA
A modulator; anxiolytic. |
| M7076
|
OBAA |
OBAA is a phospholipase A
2 inhibitor. |
