M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7148
|
PNU 22394 hydrochloride |
PNU 22394 hydrochloride is a 5-HT
2C agonist and 5-HT
2A/2B partial agonist. |
| M7147
|
PMPA (NMDA antagonist) |
PMPA (NMDA antagonist) is a competitive NMDA antagonist. |
| M7146
|
PLX 647 dihydrochloride |
PLX 647 dihydrochloride is a potent dual Fms/KIT inhibitor. |
| M7144
|
PK-THPP |
PK-THPP is a potent K
2P9.1 (TASK-3) channel blocker. |
| M7143
|
PK 44 phosphate |
PK 44 phosphate is a potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor. |
| M7142
|
PIT 1 |
PIT 1 is a pIP
3 antagonist. Blocks PIP
3-PH interaction; inhibits Akt signaling. |
| M7140
|
PIM-1 Inhibitor 2 |
PIM-1 Inhibitor 2 is a pim-1 kinase inhibitor. |
| M7138
|
PHP 501 trifluoroacetate |
PHP 501 trifluoroacetate is a potent GABA
A antagonist. |
| M7134
|
Phenserine |
Phenserine is a cholinesterase inhibitor. |
| M7129
|
PG 01037 dihydrochloride |
PG 01037 dihydrochloride is a d
3 receptor selective antagonist. |
| M7127
|
PFM 01 |
PFM 01 is a mRE11 endonuclease inhibitor. |
| M7125
|
PF 945863 |
PF 945863 is a macrolide antibiotic. |
| M7124
|
PF 750 |
PF 750 is a selective FAAH inhibitor. |
| M7121
|
PF 4778574 |
PF 4778574 is a positive allosteric modulator of AMPA receptors. |
| M7120
|
PF 06465469 |
PF 06465469 is a potent ITK inhibitor; also inhibits BTK. |
| M7118
|
PF 06273340 |
PF 06273340 is a potent and selective pan-Trk inhibitor; peripherally restricted. |
| M7117
|
PF 05190457 |
PF 05190457 is a high affinity and selective ghrelin receptor inverse agonist. |
| M7114
|
PF 04449613 |
PF 04449613是一种有效的PDE9抑制剂;大脑渗透。 |
| M7113
|
PF 04217903 mesylate |
PF 04217903 mesylate is a highly selective MET inhibitor. |
| M7109
|
Penitrem A |
Penitrem A is a potent and selective BK
Ca (K
Ca1.1) channel blocker. |
