M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M7236
|
S 18986 |
S 18986 is a positive allosteric modulator of AMPA. |
| M7235
|
Ryuvidine |
Ryuvidine is a sETD8 inhibitor; also CDK4 inhibitor. |
| M7233
|
RWJ 52353 |
RWJ 52353 is a α
2D agonist. |
| M7232
|
RWJ 50271 |
RWJ 50271 is a inhibitor of LFA-1/ICAM mediated cell adhesion. |
| M7231
|
RWJ 21757 |
RWJ 21757 is a toll-like receptor 7 (TLR7) agonist. |
| M7230
|
RuBi-4AP |
RuBi-4AP is a caged 4-aminopyridine; a non-selective K
V channel blocker. |
| M7229
|
RU 58668 |
RU 58668 is a pure antiestrogen. |
| M7228
|
RU 28318, potassium salt |
RU 28318, potassium salt is a potent, selective mineralocorticoid receptor antagonist. |
| M7225
|
RS 56812 hydrochloride |
RS 56812 hydrochloride is a 5-HT
3 partial agonist. |
| M7223
|
RS 45041-190 hydrochloride |
RS 45041-190 hydrochloride is a high affinity I
2 ligand. Highly selective. |
| M7222
|
RS 25344 hydrochloride |
RS 25344 hydrochloride is a potent PDE4 inhibitor. |
| M7221
|
RS 23597-190 hydrochloride |
RS 23597-190 hydrochloride is a 5-HT
4 antagonist. |
| M7220
|
RS 17053 hydrochloride |
RS 17053 hydrochloride is a α
1A antagonist. |
| M7219
|
RS 127445 hydrochloride |
RS 127445 hydrochloride is a selective, high affinity 5-HT
2B antagonist. |
| M7217
|
RS 100329 hydrochloride |
RS 100329 hydrochloride is a potent, subtype-selective α
1A antagonist. |
| M7213
|
Roxindole hydrochloride |
Roxindole hydrochloride is a dopamine D
2 autoreceptor agonist. Also has affinity for D
3, D
4, 5-HT
1A receptors and the 5-HT transporter. |
| M7212
|
ROS 234 dioxalate |
ROS 234 dioxalate is a potent H
3 antagonist. |
| M7211
|
Ro 67-7476 |
Ro 67-7476 is a positive allosteric modulator of mGlu
1. |
| M7210
|
Ro 64-5229 |
Ro 64-5229 is a selective, non-competitive mGlu
2 antagonist. |
| M7208
|
Ro 32-3555 |
Ro 32-3555 is a potent, collagenase-selective MMP inhibitor. |
