Cytokines and Growth Factors 细胞因子/生长因子 Cytokines and Growth Factors

目录号 产品名称 产品简介
M9370 Recombinant Human TNF α (HEK293, C-His) 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml
M9391 Recombinant Human TGF-β1 (CHO) 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。
M9241 Recombinant Human EPO Protein (CHO) 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。
M9987 Recombinant Human PDGF-AA Protein (HEK293) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M9981 Recombinant Human IL-11 Protein (E. coli) 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。
M21094 Recombinant Rat IL-1β (E. coli) 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
M10022 Recombinant Mouse GM-CSF Protein (CHO) 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。
M31138 Recombinant Mouse R-spondin-2/RSPO2 Protein (HEK293, mFc) R-spondin 2(RSPO2)蛋白是R-spondin蛋白质家族的重要成员。RSPO2是Wnt信号通路的激活剂和BMP信号通路的抑制剂。RSPO2具有促进细胞增殖和分化的能力,是类器官培养的常用细胞因子之一。
M31137 Recombinant Mouse R-spondin 1/RSPO1 Protein (CHO, C-His) R-spondin 1(RSPO1)蛋白,是一种重要的细胞因子,R-spondin 1可以通过增强Wnt信号通路来促进多种细胞的增殖和分化。R-spondin 1是多种类器官培养中不可或缺的一种蛋白。
M31133 Recombinant Mouse FGF-10/KGF-2 Protein (E. coli) Fibroblast Growth Factor-10 (FGF-10, also known as KGF-2) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions.
M31115 Recombinant Mouse CD28 (HEK293, C-Fc-6His) CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86.
M31112 Recombinant Human IL-21 Protein (E. coli) IL-21 is expressed by CD4+ T cells, natural killer (NK) T cells, and Th17 cells. IL-21 plays a pivotal role in the survival and proliferation of B cells, and their differentiation to immunoglobulin (Ig) producing cells.
M31084 Recombinant Mouse IL-2 Protein (E. coli) Interleukin-2/IL-2 is a secreted protein that belongs to the IL-2 family. Interleukin-2/IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Interleukin-2 / IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
M25587 Recombinant Mouse CXCL13/BCA-1 Protein (HEK293, N-Fc) CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles). Recombinant Mouse CXCL13/BCA-1 Protein is produced by HEK293 expression system with a N-Terminal Fc-tag.
M25579 Recombinant Human IL6 (P.pastoris) 重组人白细胞介素6(IL-6)是由毕赤酵母菌表达纯化的一种多功能的细胞因子,具有刺激活化B细胞增殖和分抗抗体,刺激T细胞增殖及CTL活化,刺激肝细胞合成急性期蛋白,参与炎症反应,以及促进血细胞发育等功能。该产品纯度高,活性强,稳定性好。
M25569 Recombinant Murine CXCL11/I-TAC Protein (E. coli) CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver.
M25568 Recombinant Human CXCL11/I-TAC Protein (E. coli) CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver.
M25538 Recombinant Human SEPHS1 (HEK293, C-6His) Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. SEPHS1 can be activated by phosphate ions and by potassium ions.
M25536 Recombinant Human CXCL13/BCA-1 (E. coli) CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml.
M25532 Recombinant Human PDGF-AA protein (E.coli) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M25530 Recombinant human Heregulin β-1 protein (CHO) Heregulin β-1蛋白,也被称为神经调节蛋白-1(NRG-1)或HRG,是一种具有多种生物活性的糖蛋白,包含一个Ig结构域和一个EGF样结构域。 Heregulin β-1可介导细胞间信号传导,并在多个器官的生长和发育中发挥关键作用。
M25484 Recombinant Human HBAZ Protein (E.coli, N-6His) Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. Recombinant Human Hemoglobin Subunit Zeta is produced by our E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus.
M25483 Recombinant Human HBQ1 Protein (E.coli, N-6His) Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Hemoglobin has a quaternary structure characteristically composed of many multi-subunit globular proteins. Recombinant Human Hemoglobin Subunit Theta-1 is produced by E.coli expression system and the target gene encoding Met1-Arg142 is expressed with a 6His tag at the N-terminus.
M25480 Recombinant Human VWF Protein (CHO, His Tag) Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury.
M25476 Recombinant Streptococcus pyogenes CRISPR-Cas9 Protein (Baculovirus-Insect, His) The recombinant s. pyogenes serotype M1 cas9 consists of 1407 amino acids and predicts a molecular mass of 163 kDa.
M25441 Recombinant Human Endothelin B Receptor Protein (HEK293, His Tag) EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. The recombinant human EDNRB consists 86 amino acids and predicts a molecular mass of 9.5 kDa. A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with a polyhistidine tag at the C-terminus.
M25440 Recombinant Human Osteopontin/SPP1 Protein (HEK293, C-6His) Osteopontin/SPP1 is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Osteopontin/SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10.








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