Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury.
别名:Von Willebrand Factor; rhvwf
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.
A DNA sequence encoding the pro form of human Von Willebrand factor (AAB59458.1) (Met1-Lys2813) was expressed with a C-terminal polyhistidine tag.
The recombinant human VWF consists of 2802 amino acids after removal of the signal peptide and has a predicted molecular mass of 308 kDa.
Endotoxin: < 1.0 EU/μg
Lyophilized from sterile PBS, pH 7.4.
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stable for up to twelve months from date of receipt at -20℃ to -80℃ |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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