Recombinant Human IL-21 Protein (E. coli) 别名：Interleukin-21; 重组人IL-21蛋白 (E. coli)

目录号 M31112

IL-21 is expressed by CD4+ T cells, natural killer (NK) T cells, and Th17 cells. IL-21 plays a pivotal role in the survival and proliferation of B cells, and their differentiation to immunoglobulin (Ig) producing cells.

Recombinant Human IL-21 Protein (E. coli)结构式

规格	价格	库存状态
10ug	¥ 2000	现货
50ug	¥ 6300	现货

*AbMole所有产品仅供有资质的科研机构或医药企业进行科学研究或药证申报用途，不能被用于人体和任何其它用途。我们不向任何个人或非科研性质的机构提供产品和服务。

质量标准及产品资料

纯度：>95%, Endotoxin < 0.2 EU/µg
COA

化学性质/溶解性/储存

性状	Lyophilized powder
中文名称	重组人IL-21蛋白 (E. coli)
溶解性	Reconstitute the lyophilized powder in ddH2O to 100 μg/ml.
储存条件	Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

生物活性

Interleukin-21 (IL-21) is expressed by CD4+ T cells, natural killer (NK) T cells, and Th17 cells. IL-21 plays a pivotal role in the survival and proliferation of B cells, and their differentiation to immunoglobulin (Ig) producing cells. IL-21 up-regulates and down-regulates the production of IgG1 and IgE by B cells, respectively, and diminishes the severity of allergy and asthma. Interleukin-21 (IL-21) belongs to the Type I four helix bundle cytokines, and shares the common cytokine receptor γ chain with IL-2, IL-4, IL-7, IL-9, and IL-15.

Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells, the ED50 is ≤ 3.0 ng/ml.

Accession # Q9HBE4

Apparent Molecular Weight ~15.4 kDa, reducing conditions

Endotoxin < 0.2 EU/μg

Lyophilized after extensive dialysis against PBS.

实验参考

动物实验

建议您制定动物给药及实验方案时，尽量参考已发表的相关实验文献（溶剂种类及配比众多，简单地溶解目的化合物，并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题，未必能保证目的化合物在动物体内充分发挥生物学效用）。
体内实验的工作液，建议您现用现配，当天使用；如在配制过程中出现沉淀、析出现象，可以通过超声和（或）加热的方式助溶。
切勿一次性将产品全部溶解。