Recombinant Mouse R-spondin-2/RSPO2 Protein (HEK293, mFc) 别名：重组小鼠R-spondin-2/RSPO2蛋白 (HEK293, mFc)

目录号 M31138

R-spondin 2（RSPO2）蛋白是R-spondin蛋白质家族的重要成员。RSPO2是Wnt信号通路的激活剂和BMP信号通路的抑制剂。RSPO2具有促进细胞增殖和分化的能力，是类器官培养的常用细胞因子之一。

Recombinant Mouse R-spondin-2/RSPO2 Protein (HEK293, mFc)结构式

规格	价格	库存状态
50ug	¥ 4995	现货

*AbMole所有产品仅供有资质的科研机构或医药企业进行科学研究或药证申报用途，不能被用于人体和任何其它用途。我们不向任何个人或非科研性质的机构提供产品和服务。

质量标准及产品资料

纯度：>85%, Endotoxin < 1 EU/µg
COA

化学性质/溶解性/储存

性状	Lyophilized powder
中文名称	重组小鼠R-spondin-2/RSPO2蛋白 (HEK293, mFc)
溶解性	Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml.
储存条件	Stable for up to 12 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式	冰袋运输，根据产品的不同，可能会有相应调整。

生物活性

R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. R-spondin-2 also acts as a ligand for frizzled and LRP receptors. The encoding gene Rspo2 was identified as a novel common integration site for the mouse mammary tumor virus in viral induced mouse mammary tumors. Rspo2 and Rspo2 / Wnt1 tumors contained many spindle cells, consistent with an epithelial-mesenchymal transformation phenotype.

The recombinant mouse Rspo2 consists 416 amino acids and predicts a molecular mass of 47.4 kDa.

A DNA sequence encoding the mouse Rspo2 (NP_766403.1) (Met1-Gly205) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Endotoxin < 1.0 EU/μg

Lyophilized from sterile PBS, pH 7.4.

实验参考

动物实验

建议您制定动物给药及实验方案时，尽量参考已发表的相关实验文献（溶剂种类及配比众多，简单地溶解目的化合物，并不能解决动物给药依从性、体内生物利用度、组织分布等相关问题，未必能保证目的化合物在动物体内充分发挥生物学效用）。
体内实验的工作液，建议您现用现配，当天使用；如在配制过程中出现沉淀、析出现象，可以通过超声和（或）加热的方式助溶。
切勿一次性将产品全部溶解。