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Recombinant Mouse IL-2 Protein (E. coli) 重组小鼠IL-2蛋白 (E. coli)

目录号 M31084 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Interleukin-2/IL-2 is a secreted protein that belongs to the IL-2 family. Interleukin-2/IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Interleukin-2 / IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Recombinant Mouse IL-2 Protein (E. coli)结构式

别名:Interleukin-2; TCGF; Aldesleukin

规格 价格 库存状态
20ug ¥ 2400 中国库存现货
100ug ¥ 6200 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >92%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

Interleukin-2/IL-2 is a secreted protein that belongs to the IL-2 family. Interleukin-2/IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Interleukin-2 / IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

The recombinant mouse IL2 consists of 150 amino acids and has a calculated molecular mass of 17.4KDa.

A DNA sequence encoding the soluble form of mouse IL2 (P04351) (Ala 21-Gln 169) was expressed, with an initial Met at the C-terminus.

Measured by cell proliferation assay using CTLL2, the ED50 for this effect is typically 6-30 ng/mL.


Accession: P04351

Molecular Weight: Approximately 19 kDa in SDS-PAGE under reducing conditions

Lyophilized from sterile PBS, 2mM DTT, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml.
储存条件 Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Natasha C Ward, et al. Diabetes. Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms

[2] Liliane Khoryati, et al. Sci Immunol. An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice

[3] Yunzhou Wu, et al. J Pharmacol Sci. Recombinant Newcastle disease virus (NDV/Anh-IL-2) expressing human IL-2 as a potential candidate for suppresses growth of hepatoma therapy

[4] Min Wei, et al. Protein Eng Des Sel. Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo

[5] T Nguyen, et al. Eur J Immunol. IL-12 enhances IL-2 function by inducing CD25 expression through a p38 mitogen-activated protein kinase pathway

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关键词:Recombinant Mouse IL-2 Protein (E. coli), Interleukin-2; TCGF; Aldesleukin, Recombinant Mouse IL-2 Protein (E. coli)供应商, Recombinant Proteins抑制剂, 购买Recombinant Mouse IL-2 Protein (E. coli), Recombinant Mouse IL-2 Protein (E. coli)溶解度, Recombinant Mouse IL-2 Protein (E. coli)结构式








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