M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M20443
|
4-Butylresorcinol |
4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC50 of 11.27 μM. |
| M20439
|
4'-Hydroxychalcone |
4'-Hydroxychalcone, found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manner and activating BMP signaling. |
| M20430
|
Adrenosterone |
Adrenosterone is endogenous steroid hormone that has been promoted as a dietary supplement capable of reducing body fat and increasing muscle mass. |
| M20429
|
4-Hydroxychalcone |
4-Hydroxychalcone is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling. |
| M20426
|
Isatin |
Isatin is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A. |
| M20420
|
L(+)-Arabinose |
L-Arabinose (l-Ara) is a plant saccharide that is not found in animals. It is a component of cell wall and may be useful as a natural pharmaceutical. |
| M20419
|
Hydroxytyrosol Acetate |
Hydroxytyrosol acetate (HTy-Ac), an extra virgin olive oil (EVOO) polyphenol, exhibits antioxidant and anti-inflammatory effects. |
| M20411
|
Flavanone |
Flavanones show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties. |
| M20405
|
Osalmid |
Osalmid suppresses ribonucleotide reductase (RR) activity in a concentration-dependent manner, with a 50% RR activity-inhibitory concentration (IC50) of 8.23 μM. |
| M20400
|
Morin Hydrate |
Morin hydrate(Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). |
| M20399
|
TAME |
Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor. |
| M20387
|
WAY-310586-A |
WAY-310586-A is a TAOK2 inhibitor. |
| M20384
|
WAY-300507 |
WAY-300507 is a beta-catenin modulator |
| M20383
|
WAY-300744 |
WAY-300744 is a kinase inhibitor. |
| M20382
|
WAY-301205 |
WAY-301205 is a Mycobacterium tuberculosis shikimate kinase inhibitor. |
| M20379
|
WAY-332647 |
WAY-332647 is a inhibitor of pyruvate kinase. |
| M20377
|
WAY-626309 |
WAY-626309 is a inhibitor of the c-Jun N-terminal kinase. |
| M20375
|
WAY-337530 |
WAY-337530 is a active CLK-1 inhibitor |
| M20374
|
WAY-337532 |
WAY-337532 is a active CLK-1 inhibitor |
| M20369
|
WAY-311753-A |
WAY-311753-A is a tyrosine kinase inhibitor. |
