M2206
|
TH-302 (Evofosfamide) |
TH-302是一种选择性低氧激活的前体药物，靶向作用于实体瘤的hypoxic区域，IC50为19 nM，在缺氧条件下比在有氧条件下细胞毒性增强270倍，细胞色素P450代谢稳定。 |
| M6098
|
Baicalein |
Baicalein（5,6,7-Trihydroxyflavone，Noroxylin，黄芩素）是一种存在于黄芩，木蝴蝶，百里香等植物中的天然黄酮类化合物，具有抗炎和抗癌活性。Baicalein可明显抑制PI3K/Akt/NF-κB途径，同时也可通过上调GPX4，抑制黑素细胞的铁死亡（ferroptosis），用于白癜风和肿瘤的相关研究。 |
| M9325
|
EGTA |
EGTA是一种特殊的钙离子螯合剂，在生理 pH 值 (7.4) 下，Kd 为 60.5 nM，对 Ca2+ 比对 Mg2+ 有很高的特异性。EGTA 显著抑制炎性巨噬细胞的底物粘附能力。 |
| M9330
|
Brij-35 |
Brij-35（月桂醇聚氧乙烯醚）是一种无毒的非离子表面活性剂，可降低非特定蛋白质的吸附，应用于红曲霉深层发酵时，能显著提高红曲色素产量。 |
| M6154
|
2-PMPA tetrasodium |
2-PMPA（PMPA tetrasodium salt）是高效选择性的谷氨酸羧肽酶II (GCPII)抑制剂，IC50值为300 pM。 |
| M2250
|
Pamidronate disodium |
Pamidronate Disodium（帕米膦酸二钠）是一种含氮的双磷酸盐类化合物，具有抑制骨吸收的作用，可用于癌症相关的溶骨性病变等研究。 |
| M9916
|
DPPH |
DPPH (2,2-Diphenyl-1-picrylhydrazyl，2,2-联苯基-1-苦基肼基) 是一种稳定的自由基，可用于测量抗氧化剂的自由基清除活性。 |
| M9194
|
Insulin (human) |
Insulin (human) 是一种多肽激素，其调节血液中的糖（葡萄糖）水平并且由胰岛的β细胞产生。 |
| M3409
|
Formestane |
Formestane（4-hydroxyandrostenedione，福美司坦）是第二代选择性芳香酶抑制剂，IC50为80 nM。 |
| M9665
|
N-(2-amino-2-oxoethyl)acrylamide |
N-(2-Amino-2-oxoethyl)acrylamide（N-acryloyl-glycinamide，丙烯酰基甘氨酰胺）是一种单体，其聚合物能制备水凝胶，并用于酶的固定化。 |
| M20662
|
Demecarium Bromide |
Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM. |
| M20661
|
Benzylacetone |
4-Phenylbutan-2-one is a model compound for the preparation of fragrances. |
| M20659
|
Coumarin 151 |
qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding |
| M20657
|
Phenylacetaldehyde |
Phenylacetaldehyde and carbon monoxide as effective additives for the selective hydrogenation of cyclooctadienes to cyclooctene over palladium catalysts.
Phenylacetaldehyde is a oviposition inhibitor for the Pink Bollworm.
Phenylacetaldehyde is a fragrant chemical compound, it can attract Moths to bladder flower and to blacklight traps. |
| M20656
|
Sequoyitol |
Effect on amyloid beta 42 aggregation assessed as inhibition of fiber formation at 5 mM |
| M20655
|
7-Hydroxy-4-methyl-8-nitrocoumarin |
Inhibition of CK2 in rat liver |
| M20654
|
6-Hydroxy-4-methylcoumarin |
Growth inhibition of human U937 cells by [3H]thymidine incorporation assay |
| M20653
|
Huperzine B |
Huperzine-B is a efficient inhibitor of human brain AChE.
Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy. |
| M20620
|
ONO-7300243 |
ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM. |
| M20611
|
MK571 |
MK-571 is a selective, orally active CysLT1 receptor(Cysteinyl leukotriene receptor) antagonist. |
| M20608
|
SecinH3 |
SecinH3 is a selective cytohesin inhibitor with IC50 of 2.4 μM, 5.4 μM, 5.4 μM, 5.6 μM, 5.6 μM, and 65 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, and yGea2-S7, respectively. |
| M20598
|
FPH2 (BRD-9424) |
FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes. |
| M20585
|
Briciclib |
Briciclib is a water soluble derivative of ON-013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E) . |
| M20584
|
kb-NB77-78 |
kb-NB77-78 is an analog of CID797718. However, it shows no inhibitory activty towards PKD1. |
| M20579
|
Iso-H7 dihydrochloride |
Iso-H7 dihydrochloride is an inhibitor of phosphokinase C . |
| M20569
|
Lazabemide |
Lazabemide is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM. |
| M20568
|
AGI 1067 |
AGI-1067 is a novel, phenolic, intra- and extracellular antioxidant that inhibits the expression of a number of proinflammatory genes involved in atherosclerosis. |
| M20566
|
Undecanedioic acid |
Undecanedioic acid is a long-chain dicarboxylic acid that has applications in corrosion inhibitors, hot melt adhesives, high performance polyamides/Nylon, and more. |
| M20563
|
4-Pentenoic acid |
4-Pentenoic acid is an endogenous metabolite. |
| M20562
|
Dodecanedioic acid |
Dodecanedioic acid is a dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitors, surfactants, and engineering plastics. |
